Results 301 to 310 of about 253,649 (335)

Erratum to 'Novel role of MHC class II transactivator in hepatitis B virus replication and viral counteraction' [Clin Mol Hepatol 2024;30:539-560]. [PDF]

Clin Mol Hepatol
Dezhbord M, Kim SH, Park S, Lee DR, Kim N, Won J, Lee AR, Kim DS, Kim KH.   +8 more
europepmc   +1 more source

Graph-pMHC: graph neural network approach to MHC class II peptide presentation and antibody immunogenicity. [PDF]

Brief Bioinform
Thrift WJ, Perera J, Cohen S, Lounsbury NW, Gurung HR, Rose CM, Chen J, Jhunjhunwala S, Liu K.   +8 more
europepmc   +1 more source

Human MHC Class II and Invariant Chain Knock-in Mice Mimic Rheumatoid Arthritis with Allele Restriction in Immune Response and Arthritis Association. [PDF]

Adv Sci (Weinh)
Romero-Castillo L, Li T, Do NN, Sareila O, Xu B, Hennings V, Xu Z, Svensson C, Oliveira-Coelho A, Sener Z, Urbonaviciute V, Ekwall O, Burkhardt H, Holmdahl R.   +13 more
europepmc   +1 more source

The generation and immunoresponsiveness of transgenic mice expressing T cell localised MHC class II

, 1997
Deborah Palliser
openalex   +1 more source

Single-cell spatial atlas of high-grade serous ovarian cancer unveils MHC class II as a key driver of spatial tumor ecosystems and clinical outcomes

Perez-Villatoro F, van Wagensveld L, Shabanova A, Junquera A, Kang Z, Niemiec I, Falco MM, Anttila E, Casado J, Marcus E, Kahelin E, Chamchougia F, Salko M, Shah S, Russo S, Chiaro J, Grönholm M, Sonke GS, Van de Vijver KK, Kruitwagen RF, Avan der Aa M, Virtanen A, Cerullo V, Vähärautio A, Sorger PK, Horlings HM, Färkkilä A.   +26 more
europepmc   +1 more source

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MHC class I and II deficiencies

Journal of Allergy and Clinical Immunology, 2014
Deficiencies of MHC complex class I or II are rare primary immunodeficiencies, both of which are inherited in an autosomal recessive pattern. MHC class II deficiency is a prototype of a disease of gene regulation. Defects in transacting regulatory factors required for expression of MHC class II genes, rather than the genes themselves, are responsible ...
Suheir Hanna, Amos Etzioni
openaire   +2 more sources

Mutations of class II MHC molecules

Immunology Today, 1987
It remains unclear how the tertiary interaction of T-cell receptor, la molecule and foreign antigen results in the extensive diversity of the helper T cell repertoire. Here Laurie Glimcher and Irwin Griffith focus on what has been learned about the relationship between structure and function of the la molecule from the use of mouse strains with ...
L H, Glimcher, I J, Griffith
openaire   +2 more sources

MHC Class-II Molecules and Autoimmunity

Annual Review of Immunology, 1991
Molecular and genetic studies of HLA class-II genes provide new insights into the basis for MHC associations with autoimmunity. Polymorphisms among class-II genes identify specific haplotypes associated with autoimmune diseases such as type-I diabetes, rheumatoid arthritis, celiac disease, and pemphigus vulgaris.
G T, Nepom, H, Erlich
openaire   +2 more sources

Regulation of Class II MHC Expression

Critical Reviews™ in Immunology, 1996
The class II genes of the major histocompatibility complex (MHC) encode the alpha/beta heterodimeric glycoproteins that play a critical role in the induction of immune responses through presentation of processed antigen to CD4+ T lymphocytes. The constitutive expression of class II MHC antigens is restricted primarily to B cells, dendritic cells ...
W M, Rohn, Y J, Lee, E N, Benveniste
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Nonclassical MHC Class II Molecules

Annual Review of Immunology, 2000
Major histocompatibility complex (MHC) class II molecules are cell surface proteins that present peptides to CD4+T cells. In addition to these wellcharacterized molecules, two other class II–like proteins are produced from the class II region of the MHC, HLA-DM (DM) and HLA-DO (DO) (called H2-M, or H2-DM and H2-O in the mouse).
C, Alfonso, L, Karlsson
openaire   +2 more sources