Results 121 to 130 of about 6,114 (196)
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Serotonin receptor sensitivity after acute and chronic treatment with mianserin.
Journal of Pharmacology and Experimental Therapeutics, 1982The chronic administration of mianserin for 14 days leads to a marked decrease in the maximal number of serotonin2 (5-HT2) binding sites in brains of rats and mice with no change in the KD values.
M. Blackshear, E. Sanders‐Bush
semanticscholar +1 more source
Journal of Pharmacology and Experimental Therapeutics, 1996
The effects of three compounds with alpha-2 adrenoceptor antagonistic properties, mirtazapine (Org 3770; Remeron), mianserin and idazoxan, were measured on hippocampal noradrenergic and serotonergic transmission in freely moving rats by using ...
T. D. Boer +3 more
semanticscholar +1 more source
The effects of three compounds with alpha-2 adrenoceptor antagonistic properties, mirtazapine (Org 3770; Remeron), mianserin and idazoxan, were measured on hippocampal noradrenergic and serotonergic transmission in freely moving rats by using ...
T. D. Boer +3 more
semanticscholar +1 more source
Journal of Pharmacology and Experimental Therapeutics, 1996
To identify cytochrome P450 (CYP) isoform(s) involved in the major metabolic pathways of mianserin (MS) enantiomers in humans, we examined the metabolites formed from S-(+)- and R-(-)-MS using human liver microsomes and eight recombinant human CYP ...
E. Koyama +3 more
semanticscholar +1 more source
To identify cytochrome P450 (CYP) isoform(s) involved in the major metabolic pathways of mianserin (MS) enantiomers in humans, we examined the metabolites formed from S-(+)- and R-(-)-MS using human liver microsomes and eight recombinant human CYP ...
E. Koyama +3 more
semanticscholar +1 more source
Effects of Intra-VMN Mianserin and IL-1ra on Meal Number in Anorectic Tumor-Bearing Rats
Journal of Investigative Medicine, 2000Background Tumor growth in animals and humans is associated with the onset of anorexia and reduced food intake. We previously demonstrated that the ventromedial nucleus of hypothalamus (VMN) plays a contributory role in mediating cancer anorexia. Because
Alessandro Laviano +5 more
semanticscholar +1 more source
Mianserin or placebo as adjuncts to typical antipsychotics in resistant schizophrenia
International Clinical Psychopharmacology, 2002The beneficial effect of atypical antipsychotic drugs (APDs) in treatment-resistant schizophrenia patients has been attributed, mostly, to their relatively high serotonergic (5-HT)2 to dopaminergic (D)2 receptor blockade ratio.
R. Shiloh +6 more
semanticscholar +1 more source
The effect of mianserin on the severity of psychosis and dyskinesia in the parkinsonian marmoset
Progress in Neuro-psychopharmacology and Biological Psychiatry, 2018Adjia Hamadjida +3 more
semanticscholar +1 more source

