A novel approach in the treatment of neuroendocrine gastrointestinal tumors: Additive antiproliferative effects of interferon-γ and meta-iodobenzylguanidine [PDF]
Background Therapeutic options to effectively inhibit growth and spread of neuroendocrine gastrointestinal tumors are still limited. As both meta-iodobenzylguanidine (MIBG) and interferon-γ (IFNγ) cause antineoplastic effects in neuroendocrine ...
Michael Höpfner +59 more
core +2 more sources
Cardiac Sympathetic Hyperactivity after Chemotherapy: Early Sign of Cardiotoxicity?
Background: Chemotherapy with anthracyclines and trastuzumab can cause cardiotoxicity. Alteration of cardiac adrenergic function assessed by metaiodobenzylguanidine labeled with iodine-123 (123I-mIBG) seems to precede the drop in left ventricular ...
Sarita Lígia Pessoa de Melo Machado Guimarães +4 more
doaj +1 more source
Normal values and within-subject variability of cardiac I-123 MIBG scintigraphy in healthy individuals: Implications for clinical studies [PDF]
Background: Although several myocardial iodine 123 metaiodobenzylguanidine (MIBG) indices are increasingly used to detect alterations in myocardial sympathetic activity in various forms of cardiac pathology, published measurements of normal values and ...
Fleury, Eric +3 more
core
Cardiac autonomic neuropathy in patients with diabetes and no symptoms of coronary artery disease: comparison of 123I-metaiodobenzylguanidine myocardial scintigraphy and heart rate variability [PDF]
The purpose of this study was to evaluate the prevalence of cardiac autonomic neuropathy (CAN) in a cohort of patients with type 2 diabetes, truly asymptomatic for coronary artery disease (CAD), using heart rate variability (HRV) and I-123 ...
Arthur J. H. A. Scholte +61 more
core +1 more source
The utility of transcranial sonography (TCS) remains unclarified for the auxiliary diagnosis of Parkinson’s disease (PD). We investigated iodine-123 metaiodobenzylguanidine (MIBG) and TCS during the examination and diagnosis of high-signal-intensity ...
Heisuke Mizukami +6 more
doaj +1 more source
Is Overexpression of the Plasma Membrane Transporter (SLC29A4) a New Option to Stratify Patients with High-Risk Neuroblastoma for Treatment with 131I-mIBG? [PDF]
Raymond Evers
openalex +1 more source
Aim Positron emission tomography (PET) using 124I-mIBG has been established for imaging and pretherapeutic dosimetry. Here, we report the first systematic analysis of the biodistribution and radiation dosimetry of 124I-mIBG in patients with neural crest ...
Alexandros Moraitis +10 more
doaj +1 more source
Targeted therapy in nuclear medicine—current status and future prospects [PDF]
In recent years, a number of new developments in targeted therapies using radiolabeled compounds have emerged. New developments and insights in radioiodine treatment of thyroid cancer, treatment of lymphoma and solid tumors with radiolabeled monoclonal ...
Bodei, L. +6 more
core
Role of Iodine-131 MIBG Scanning in the Management of Paediatric Patients with Neuroblastoma [PDF]
Ghulam Syed +3 more
openalex +1 more source
Cardiac 123I-MIBG uptake in de novo Brazilian patients with Parkinson's disease without clinically defined dysautonomia [PDF]
Marco Antônio Araújo Leite +7 more
openalex +1 more source

