Results 151 to 160 of about 336,883 (343)

Population pharmacokinetics of TBAJ‐587 and its main metabolites—Evaluation of different loading dose strategies and early dose selection

British Journal of Clinical Pharmacology, EarlyView.
Background and Aim The rise of drug‐resistant tuberculosis (TB) poses a need for new drugs and combinations. TBAJ‐587, a new diarylquinoline (DARQ), has shown promising efficacy in preclinical studies. This work aimed to describe the pharmacokinetics (PK) of TBAJ‐587 and its metabolites M2 and M3 after single ascending dosing in healthy volunteers and ...
Albin A. M. Leding, Paul Bruinenberg, Almari Conradie, Jerry Nedelman, Antonio Lombardi, Dean Hickman, Ulrika S. H. Simonsson   +6 more
wiley   +1 more source

Systematic review of antimicrobial pharmacokinetic/pharmacodynamic indices in murine thigh and hollow fibre dose fractionation studies analysed with a standard method. [PDF]

J Antimicrob Chemother
Alabdulkarim N, Readman J, Mead A, Oakley R, Wenker S, Kembou J, Azzariti S, Bajaj-Elliott M, Cortina-Borja M, Standing JF.   +9 more
europepmc   +1 more source

Refractory Infective Endocarditis Due to MRSA which Vancomycin MIC Changed　During Antimicrobial Therapy

, 2013
Keitaro Arima, Keiji Tsuchiya, Mizuhiko Ishigaki, Yoshio Imada   +3 more
openalex   +2 more sources

‘The best year’/‘I struggled with everything’: Widening participation experiences of pandemic online learning

British Educational Research Journal, EarlyView.
Abstract Improving retention and graduate outcomes for students from a widening participation (WP) background is key to achieving more equitable outcomes. However, evidence suggests WP students experienced different challenges than their peers during the COVID‐19 pandemic.
Wilhelmiina Toivo, Emily Nordmann, Jacqui Hutchison, Alison Browitt, Jill R. D. MacKay   +4 more
wiley   +1 more source

Effect of Methyl Isocyanate (MIC) Gas on the Eyes of Fischer 344 Rats

, 1987
B. N. Gupta, Steven A. Stefanski, J. R. Bucher, L. B. Hall   +3 more
openalex   +1 more source

A pH‐responsive charge‐reversal liposome with enhanced biofilm penetration for multimodal synergistic therapy of bacterial infections

BMEMat, EarlyView.
This study develops a pH‐responsive, charge‐reversal liposome for treating bacterial biofilm infections. With enhanced penetration capability, the liposome effectively delivers antibacterial agents into biofilms. By integrating photodynamic and photothermal therapies with antibiotics, it significantly eradicates biofilms and accelerates bacteria ...
Ruyue Li, Bo Liu, Cheng Wang, Zhencheng Sun, Shuyi Lv, Liang Tian, Minghui Xiao, Qinyang Zheng, Linqi Shi, Chunlei Zhu   +9 more
wiley   +1 more source

Reconsidering vancomycin trough targets in critically-ill patients. [PDF]

Crit Care
Movahedan M, Lee C, Leung V.
europepmc   +1 more source

Different Responses of MSSA and MRSA to Oxacillin of Their Respective MICs [PDF]

, 2009
Jong-Soon Jung, Woon-Seob Shin, Soo‐Ki Kim, Yoon Sun Park   +3 more
openalex   +1 more source

Survey Comics and Education. ICOn MICs CA19119 Validation 2021

, 2022
José Rovira-Collado, Olga Nowak
openalex   +1 more source

Cutting edge strategies for diabetic wound care: Nanotechnology, bioengineering, and beyond

BMEMat, EarlyView.
Graphical abstract illustrates the challenges in diabetic wound healing, covering pathophysiology, formulation hurdles, and emerging therapeutic strategies. It highlights the role of hyperglycemia, formulation complexities, and advanced technologies like bioprinting and AI in improving diabetic wound management. Abstract Diabetic wounds affect millions
Usama Ahmad, Wan Nurhidayah Wan Hanaffi, Anas Islam, Aimen Salman, Mohd Muazzam Khan, Faiyaz Shakeel, Qiang Cai, Xiaojun Cai, Quazi T. H. Shubhra   +8 more
wiley   +1 more source