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MIC-A polymorphism in Japanese and a MIC-A-MIC-B null haplotype

Immunogenetics, 1999
A polymorphic gene, MIC-A, is one of the MIC family of genes which is composed of a group of homologous genes interspersed in the class III and class I regions of the major histocompatibility complex. MIC-A is located 46 kilobases (kb) centromeric of HLA-B, and is preferentially expressed in the epithelial cells and intestinal mucosa.
Yoshihide Ishikawa   +2 more
exaly   +3 more sources

Significant increase in MIC-A and MIC-B and soluble MIC-A and MIC-B in canine lymphomas

Veterinary Immunology and Immunopathology, 2023
Non-Hodkin's lymphoma (NHL) is the most frequent hematologic malignancy in humans and dogs. NKG2D is one of the most critical receptors on NK cells, recognizing their natural ligands on malignant cells such as A and B major histocompatibility complex-related proteins (MIC-A and MIC-B).
Maresa Lopez-Montaño   +6 more
openaire   +2 more sources

Of MICs and Men

New England Journal of Medicine, 2018
In medicine, we often collect data that lie on a quantitative spectrum. However, dealing with shades of gray is always complex.
openaire   +2 more sources

An economic approach to the MIC

Zentralblatt für Bakteriologie, 1996
The determination of the Inhibitory Concentration in Diffusion (ICD) is proposed as an alternative to the agar dilution Minimal Inhibitory Concentration (MIC) that is time-consuming and cumbersome for routine use. Based on the technique of the disk diffusion test, it consists in calculating a continuous variable, the ICD, corresponding to the ...
Delignette-Muller, M.   +2 more
openaire   +3 more sources

MIC-A polymorphism and a MIC-A-MIC-B null haplotype with ~ 100-kb deletion

2000
The MHC class I chain-related gene (MIC) family has been identified as a new gene family in the HLA-B region. MIC-A shows a high degree of polymorphism, and more than 30 alleles have been reported. In the present study, we analyzed the polymorphisms of exons 2, 3, and 4, which encode αl, α2, and α3 domains, using PCR-single-strand conformation ...
Miki Komatsu-Wakui   +9 more
openaire   +1 more source

MIC Myths - Does Pitting Cause MIC?

CORROSION 1998, 1998
Abstract It is widely accepted that sulfate reducers, acid producers, metal oxidizers and certain other bacteria can contribute to corrosion. However, it is far from clear how biological activity influences corrosion processes, how much metal loss is caused by bacteria, and most importantly, how microbial attack can be differentiated ...
openaire   +1 more source

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