Results 211 to 220 of about 104,211 (250)

Protective role of Galectin‐3 in prion disease through regulation of microglial PrPSc uptake

open access: yesBrain Pathology, EarlyView.
Galectin‐3 (Gal3) is induced in reactive microglia during prion disease and promotes microglial uptake of PrPSc. Gal3 deficiency reduces prion sequestration and accelerates disease progression, revealing a protective role for Gal3. Abstract Microglia constitute a major innate defense mechanism against prion infection; however, the molecular pathways ...
Natallia Makarava   +8 more
wiley   +1 more source

tRNA‐Derived Small RNAs in Digestive Cancers: From Translational Regulation to Immune and Extracellular Communication

open access: yesCancer Science, EarlyView.
tRNA‐derived small RNAs (tsRNAs) function in digestive cancers across three scales: intracellular translational and metabolic control, extracellular vesicle–mediated immune remodeling, and systemic and host–microbe communication. This review organizes these mechanisms by evidence strength, from well‐established intracellular roles to emerging ...
Wang Xitan, Li Han
wiley   +1 more source

Polymer-free van der Waals assembly of 2D material heterostructures using muscovite crystals. [PDF]

open access: yesNat Commun
Babich I   +16 more
europepmc   +1 more source

Treatment‐Free Remission in Chronic Myeloid Leukemia: Toward Precision and Personalized Approaches to Functional Cure

open access: yesCancer Science, EarlyView.
Immune surveillance of residual leukemic stem cells after tyrosine kinase inhibitor discontinuation involves coordinated NK‐cell, CTL, Treg, pDC, and neutrophil activity that predicts treatment‐free remission, while exhausted CTLs and Treg expansion predict relapse in chronic myeloid leukemia.
Hiroshi Ureshino, Shinya Kimura
wiley   +1 more source

Influence of Laser Repetition Rate, Fluence and Spot Size on LA‐Q‐ICP‐MS/MS 87Sr/86Sr Precision: Insights from Apatites and Silicate Glasses

open access: yesGeostandards and Geoanalytical Research, EarlyView.
Key Points Higher laser repetition rate, fluence and larger spot size increase signal intensity. Higher laser repetition rate produces overlaps in aerosolised particles, improving signal stability and precision. For Sr‐rich materials, moderate spot diameter (≤ 60 μm), 3 J cm‐2 fluence and ≥ 12 Hz repetition rate are recommended.
Edafe O. Ominigbo   +4 more
wiley   +1 more source

Appraisal of Six Natural Mica Reference Materials for In Situ Rb‐Sr Geochronology

open access: yesGeostandards and Geoanalytical Research, EarlyView.
Key Points Evaluated six natural mica reference materials for in situ LA‐ICP‐MS/MS Rb‐Sr geochronology using geochemical, microstructural and isotopic characterisation. Identified robust primary reference materials: Mount Dromedary biotite (99.37 Ma) and Mica‐Fe biotite (307.75 Ma). La Posta biotite and Högsbo muscovite are suitable secondary reference
Hugo K.H. Olierook   +38 more
wiley   +1 more source

Understanding the role of non-HLA antibodies in kidney transplantation: a literature review. [PDF]

open access: yesFront Immunol
Ryeed R   +6 more
europepmc   +1 more source

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