Study of the Effect of Linoleic Acid on the Expression Level of MicroRNA-106b and MicroRNA-20a and their Related Target MHC Class I Chain-related Protein A in Docetaxel-treated Gastric Cancer Cells [PDF]
Middle East Journal of Cancer, 2021 Background: MicroRNAs are involved in response to therapeutic agents and have the ability to regulate the expression level of the targets associated with cancer growth and progression.
Najibeh Shekari +6 more
doaj +1 more source
The IMiDs targets IKZF-1/3 and IRF4 as novel negative regulators of NK cell-activating ligands expression in multiple myeloma [PDF]
, 2015 Immunomodulatory drugs (IMiDs) have potent anti-tumor activities in multiple myeloma (MM) and are able to enhance the cytotoxic function of natural killer (NK) cells, important effectors of the immune response against MM.
Abruzzese, MARIA PIA +12 more
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Journal of Immunotherapy for Cancer, 2019 BackgroundImmunotherapies still fail to benefit colorectal cancer (CRC) patients. Relevant functional assays aimed at studying these failures and the efficacy of cancer immunotherapy in human are scarce.
T. Courau +10 more
semanticscholar +1 more source
High-Throughput MICA/B Genotyping of Over Two Million Samples: Workflow and Allele Frequencies
Frontiers in Immunology, 2020 MICA and MICB are ligands of the NKG2D receptor and thereby influence NK and T cell activity. MICA/B gene polymorphisms, expression levels and the amount of soluble MICA/B in the serum have been linked to autoimmune diseases, infections, and cancer.
A. Klussmeier +12 more
semanticscholar +1 more source
Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation [PDF]
, 2014 NKG2D plays a major role in controlling immune responses through the regulation of natural killer (NK) cells, αβ and γδ T-cell function. This activating receptor recognizes eight distinct ligands (the MHC Class I polypeptide-related sequences (MIC) A ...
A Dolan +98 more
core +5 more sources
RNA Biology, 2019 One key to malignant progression of pancreatic cancer (PC) is the acquired ability of tumour cells to escape immune-mediated lysis. Hypoxic microenvironment plays a causal role in PC metastasis.
Z. Ou +5 more
semanticscholar +1 more source
Ultramafic xenoliths from the Bearpaw Mountains, Montana, USA: evidence for multiple metasomatic events in the lithospheric mantle beneath the Wyoming craton [PDF]
, 2004 Ultramafic xenoliths in Eocene minettes of the Bearpaw Mountains volcanic field (Montana, USA), derived from the lower lithosphere of the Wyoming craton, can be divided based on textural criteria into tectonite and cumulate groups. The tectonites consist
Bodinier, J.L. +8 more
core +5 more sources
Human monoclonal islet specific autoantibodies share features of islet cell and 64 kDa antibodies [PDF]
, 1993 The first human monoclonal islet cell antibodies of the IgG class (MICA 1-6) obtained from an individual with Type 1 (insulin-dependent) diabetes mellitus were cytoplasmic islet cell antibodies selected by the indirect immunofluorescence test on pancreas
DJ Garry +19 more
core +1 more source
NeuroImage, 2021 Since accurate quantification of 2-deoxy-2–18F-fluoro-D-glucose ([18F]FDG) positron emission tomography (PET) requires dynamic acquisition with arterial input function, more practical semi-quantitative (static) approaches are often preferred.
Daniele Bertoglio +5 more
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