Results 21 to 30 of about 63,782 (259)

The imprint of hydrothermal fluids on trace-element contents in white mica and tourmaline from the Panasqueira W–Sn–Cu deposit, Portugal

Mineralium Deposita, 2020
White mica and tourmaline are the dominant hydrothermal alteration minerals at the world-class Panasqueira W–Sn–Cu deposit in Portugal. Thus, understanding the controls on their chemical composition helps to constrain ore formation processes at this ...
M. Codeço, P. Weis, R. Trumbull, Vincent Van Hinsberg, F. Pinto, P. Lecumberri-Sanchez, A. Schleicher   +6 more
semanticscholar   +1 more source

Cocultures of human colorectal tumor spheroids with immune cells reveal the therapeutic potential of MICA/B and NKG2A targeting for cancer treatment

Journal of Immunotherapy for Cancer, 2019
BackgroundImmunotherapies still fail to benefit colorectal cancer (CRC) patients. Relevant functional assays aimed at studying these failures and the efficacy of cancer immunotherapy in human are scarce.
Tristan Courau, J. Bonnereau, J. Chicoteau, H. Bottois, R. Remark, Laura Assante Miranda, A. Toubert, M. Bléry, T. Aparicio, M. Allez, L. Le Bourhis   +10 more
semanticscholar   +1 more source

Restorative Power of Empathetic Communication for Participatory Governance and Community Well-Being

International Journal of Communication, 2023
Our study unravels the interrelationship between empathetic communication, participatory governance, and community well-being during crises such as the pandemic.
Himani Sharma, Varsha Jain, Emmanuel Mogaji, Anantha Babbili   +3 more
doaj   +2 more sources

Urdoxa, le deepfake d’information comme usage tactique du vague : La sémiotique au défi de l’évidence

Interfaces Numériques, 2022
Cet article voudrait aborder la question du deepfake d’information en le positionnant face aux exigences de la sémiotique pragmatique américaine. Signe d’évidence, croyance fondamentale (urdoxa) le visage soumis au deepfake joue avec le réel, la vérité ...
Maxime FABRE
doaj   +1 more source

Hypoxia-induced shedding of MICA and HIF1A-mediated immune escape of pancreatic cancer cells from NK cells: role of circ_0000977/miR-153 axis

RNA Biology, 2019
One key to malignant progression of pancreatic cancer (PC) is the acquired ability of tumour cells to escape immune-mediated lysis. Hypoxic microenvironment plays a causal role in PC metastasis.
Z. Ou, Zhen Luo, Wei Wei, Shuai Liang, T. Gao, Ye-bin Lu   +5 more
semanticscholar   +1 more source

Effects of metformin on tumor hypoxia and radiotherapy efficacy: a [18F]HX4 PET imaging study in colorectal cancer xenografts

EJNMMI Research, 2019
Background In a colorectal cancer xenograft model, we investigated the therapeutic effect of metformin on tumor hypoxia with [18F]flortanidazole ([18F]HX4) small-animal positron emission tomography (μPET).
Sven De Bruycker, Christel Vangestel, Steven Staelens, Leonie wyffels, Jan Detrez, Marlies Verschuuren, Winnok H. De Vos, Patrick Pauwels, Tim Van den Wyngaert, Sigrid Stroobants   +9 more
doaj   +1 more source

High-Throughput MICA/B Genotyping of Over Two Million Samples: Workflow and Allele Frequencies

Frontiers in Immunology, 2020
MICA and MICB are ligands of the NKG2D receptor and thereby influence NK and T cell activity. MICA/B gene polymorphisms, expression levels and the amount of soluble MICA/B in the serum have been linked to autoimmune diseases, infections, and cancer.
A. Klussmeier, C. Massalski, K. Putke, G. Schäfer, J. Sauter, D. Schefzyk, J. Pruschke, J. Hofmann, D. Fürst, R. Carapito, S. Bahram, A. Schmidt, V. Lange   +12 more
semanticscholar   +1 more source

A Bioinspired Ultratough Multifunctional Mica-Based Nanopaper with 3D Aramid Nanofiber Framework as an Electrical Insulating Material.

ACS Nano, 2019
The rapid development of modern electrical equipment toward miniaturization and high power puts forward stringent requirements to the mechanical reliability, dielectric property, and heat resistance of electrical insulating materials.
F. Zeng, Xian-hong Chen, Guang Xiao, Hao Li, Shuang Xia, Jianfeng Wang   +5 more
semanticscholar   +1 more source

Restoration of antitumor immunity through anti-MICA antibodies elicited with a chimeric protein

Journal for ImmunoTherapy of Cancer, 2020
Background Natural killer and cytotoxic CD8+ T cells are major players during antitumor immunity. They express NKG2D, an activating receptor that promotes tumor elimination through recognition of the MHC class I chain-related proteins A and B (MICA and ...
Nicolás I Torres, M. V. Regge, Florencia Secchiari, A. Friedrich, R. Spallanzani, X. L. Raffo Iraolagoitia, S. Y. Nuñez, Jessica Sierra, A. Ziblat, M. C. Santilli, N. Gilio, E. Almada, Constanza Lauché, R. Pardo, C. Domaica, M. Fuertes, K. Madauss, K. Hance, I. Gloger, V. Zylberman, F. Goldbaum, N. Zwirner   +21 more
semanticscholar   +1 more source

Major Histocompatibility Complex Class I-Related Chain A (MICA) Allelic Variants Associate With Susceptibility and Prognosis of Gastric Cancer

Frontiers in Immunology, 2021
Gastric cancer (GC) is the fifth most prevalent type of cancer worldwide. Gastric tumor cells express MICA protein, a ligand to NKG2D receptor that triggers natural killer (NK) cells effector functions for early tumor elimination.
Karen Toledo-Stuardo, Carolina H. Ribeiro, Andrea Canals, Andrea Canals, Marcela Morales, Valentina Gárate, Jose Rodríguez-Siza, Samantha Tello, Marco Bustamante, Ricardo Armisen, Douglas J. Matthies, Gerald Zapata-Torres, Patricio González-Hormazabal, María Carmen Molina   +13 more
doaj   +1 more source