Results 291 to 300 of about 481,437 (386)

Middle to Late Pleistocene landscape evolution and glacial dynamics in the Eastern Alps: the Gröbminger Mitterberg record, Austria

Boreas, EarlyView.
Glacial erosion during the Last Glacial Maximum (LGM) has removed much evidence of earlier glaciations and interglacials in the European Alps. At Gröbminger Mitterberg (GM), beneath a blanket of LGM till, a distinctive sediment archive preserves deposits predating the LGM.
Gerit E. U. Griesmeier, Daniel P. Le Heron, Christopher Lüthgens, Gustav Firla, Bernhard Salcher, Fabian Dremel, Jan‐Christoph Otto, Jürgen M. Reitner   +7 more
wiley   +1 more source

Colorectal cancer organoids drive hypoxia, TGF-β, and patient-specific diversification of NK cell activation programs. [PDF]

J Immunother Cancer
von Kries A, Garcés-Lázaro I, Balzasch BM, Sticht C, Shaltiel IA, Boonekamp KE, Sams A, Triassi A, Hofman T, Burgermeister E, Betge J, Ebert M, Boutros M, Helming L, Stojanovic A, Cerwenka A.   +15 more
europepmc   +1 more source

Debris at the edge: sedimentological dynamics of Hintereisferner's evolving terminus and glacial forefield, Austrian Alps

Boreas, EarlyView.
The interaction between glaciers and the debris accumulating on their surfaces is critical as the Earth warms, with consequences for ice dynamics, hydrology and mass balance together with slope and sedimentary processes. Understanding this interaction is necessary since it influences ablation rates, sediment and meltwater pathways.
Paulina Mejías Osorio, Ricarda Wohlschlägl, Thomas M. Vandyk, Sara Karbacher, Bethan Joan Davies, Daniel Paul Le Heron   +5 more
wiley   +1 more source

Alteration of dioctahedral micas in soils

, 1961
M. G. Cook
openalex   +1 more source

Sacrifice-layer-free transfer of wafer-scale atomic-layer-deposited dielectrics and full-device stacks for two-dimensional electronics. [PDF]

Nat Commun
He Y, Lv Z, Liu Z, Yang M, Ai W, Chen J, Chen W, Wang B, Fu X, Luo F, Wu J.   +10 more
europepmc   +1 more source

MET Enhances Amivantamab Binding to EGFR and Antibody‐Dependent Cellular Toxicity

Cancer Science, EarlyView.
Amivantamab binds to EGFR domain 3 and the MET Sema domain, and the EGFR‐MET‐amivantamab trimer was successfully visualized using high‐speed atomic force microscopy (HS‐AFM). MET enhances the binding of amivantamab to EGFR and increases antibody‐dependent cellular cytotoxicity (ADCC) even at low concentrations of amivantamab.
Shigeki Sato, Neval Yilmaz, Sachiko Arai, Katsuya Sakai, Hiroki Sato, Yuya Murase, Tsukasa Ueda, Hayato Koba, Shigeki Nanjo, Yuichi Tambo, Hiroshi Kotani, Koji Fukuda, Hiroaki Taniguchi, Romain Amyot, Holger Flechsig, Hideko Isozaki, Kunio Matsumoto, Seiji Yano   +17 more
wiley   +1 more source

Non-human leukocyte antigen antibodies in kidney transplantation: pathogenic mechanisms, detection methods, and clinical implications. [PDF]

Clin Transplant Res
Oh I, Song EY.
europepmc   +1 more source

Hydrophobic residues in the α‐synuclein NAC domain drive seed‐competent fibril formation and are targeted by peptide inhibitors

The FEBS Journal, EarlyView.
The hydrophobic 68GAVV71 stretch in the NAC domain of α‐synuclein is essential for nucleation, while residues 79–95 are required for fibril stability and seeding. Truncation or inhibition of 68GAVV71 prevents fibril formation, and truncation of 79–95 abolishes seeding competency, highlighting their distinct roles in α‐synuclein aggregation and ...
Viswanath Das, Sayed Mostafa Modarres Mousavi, Narendran Annadurai, Sunčica Sukur, Faramarz Mehrnejad, Sajad Moradi, Lukáš Malina, Markéta Kolaříková, Vaclav Ranc, Ivo Frydrych, Roman Kouřil, Saman Hosseinkhani, Marián Hajdúch, Maryam Nikkhah   +13 more
wiley   +1 more source

Mechanically Tunable Néel Temperature in a 3D Nickel Oxide-Intercalated Muscovite Mesocrystal. [PDF]

Inorg Chem
Chen BS, Chen YC, Lin YT, Chen YC, Liu CE, Chen CY, Kuo CY, Liu HJ, Wang TW, Liu PL, Lai CH, Chueh YL, Chu YH.   +12 more
europepmc   +1 more source

The fc fragment of IgMs binds C1q to activate the first step of the classical complement pathway, while inhibiting complement‐dependent cytotoxicity

The FEBS Journal, EarlyView.
Multimeric IgM‐fragment crystallizable region (Fc) fragments retain the ability to bind C1q and initiate the classical complement pathway, leading to C4 activation and deposition in vitro. However, the Fc cores can also inhibit complement‐dependent cytotoxicity by competing with surface‐bound antibodies for C1q engagement.
Andrea J. Pinto, Anne Chouquet, Isabelle Bally, Véronique Rossi, Nicole M. Thielens, Chantal Dumestre‐Pérard, Renate Kunert, Christine Gaboriaud, Wai Li Ling, Jean‐Baptiste Reiser   +9 more
wiley   +1 more source