Results 191 to 200 of about 310,492 (230)

Ethanol tolerance and withdrawal responses in GABA(A) receptor alpha 6 subunit null allele mice and in inbred C57BL/6J and strain 129/SvJ mice.

Alcoholism: Clinical and Experimental Research, 1998
We have been using a genetic strategy to define the contribution of specific candidate genes, such as those encoding subunits of the gamma-aminobutyric acid type A receptor, to various ethanol sensitive responses.
G. Homanics, Nam Q. Le, F. Kist, R. Mihalek, Alison R. Hart, Joseph J. Quinlan   +5 more
semanticscholar   +1 more source

Progressive cognitive impairment and anxiety induction in the absence of plaque deposition in C57BL/6 inbred mice expressing transgenic amyloid precursor protein

Journal of Neuroscience Research, 2004
Numerous transgenic mouse models for Alzheimer's disease (AD) have been generated to recapitulate the histological pathogenesis and behavioral phenotypes of AD brain.
Kang‐Woo Lee, S. Lee, Hyuck Kim, Jin-Sook Song, Sung-Don Yang, S. Paik, P. Han   +6 more
semanticscholar   +1 more source

Behavioural and neuroanatomical divergence between two sublines of C57BL/6J inbred mice

Behavioural Brain Research, 1991
Male mice of strains C57BL/6J and DBA/2J differ reproducibly in a number of behaviours displayed in an open-field. In particular, C57BL/6J mice show a higher rearing-up frequency than do DBA/2J animals. Recently, a marked drop occurred in the frequency with which this behaviour is displayed by the C57BL/6J//Nmg (N) subline, that has been separated from
J. H. F. van Abeelen, Wim E. Crusio, Herbert Schwegler   +2 more
openaire   +3 more sources

Different effect of chronic stress on learning and memory in BALB/c and C57BL/6 inbred mice: Involvement of hippocampal NO production and PKC activity

Stress, 2009
Nitric oxide (NO) has been involved in many pathophysiological brain processes. Recently, we showed that neuronal nitric oxide synthase (nNOS)-mediated decrease in NO production is involved in memory impairment induced by chronic mild stress (CMS) in ...
M. L. Palumbo, M. Z. Zorrilla Zubilete, G. Cremaschi, A. Genaro   +3 more
semanticscholar   +1 more source

Circadian variation in concentrations of testosterone in the plasma of male mice: a difference between BALB/cBy and C57BL/6By inbred strains.

Journal of Endocrinology, 1980
Diurnal variations in testosterone in plasma were studied in two inbred strains of mice, BALB/cBy and C57BL/6By. Blood was taken every 4 h over 24 h from male mice at 70 days of age using a lighting regimen of 12 h light t 12 h darkness (lights on 07.00 ...
L. A. Lucas, B. Eleftheriou
semanticscholar   +1 more source

Alveolar Process Anabolic Activity in C3H/HeJ and C57BL/6J Inbred Mice

Journal of Periodontology, 2008
Background: The purpose of this study was to characterize bone activity of the alveolar process in C3H/HeJ (C3H) and C57BL/6J (B6) inbred mice. Based on observations in other animal species, we hypothesized that the bone‐formation rate/bone surface (BFR/BS) is greater in the alveolar process compared to the body of the mandible and that the bone ...
Parul Gulati, Isaac F. Meta, Sarandeep S. Huja, Soledad Fernandez   +3 more
openaire   +3 more sources

Antigenic differences between male and female mice of the inbred C57BL line [PDF]

Bulletin of Experimental Biology and Medicine, 1963
A method of anaphylaxis with desensitization was used to show on guinea pigs the presence of sex-linked antigens in the kidney and liver tissues of male mice (C57BL inbred strain). In the majority of the guinea pigs there occurred anaphylactic shock symptoms in response to the injection of the antigen of male mice.
openaire   +1 more source

A behavioral and neuroanatomical assessment of an inbred substrain of 129 mice with behavioral comparisons to C57BL/6J mice

Brain Research, 1999
The inbred 129 substrains have been characterized as poor learners that display hypoplasia of the corpus callosum. However, they are used extensively as a source of embryonic stem (ES) cells for creating mice carrying altered copies of a targeted gene ('knockout mice'). The present research investigated callosal agenesis and behavior in the 129/SvEvTac
Victor H. Denenberg, Amy Jo Stavnezer, Seth A. Balogh, Cary S McDowell   +3 more
openaire   +3 more sources

Susceptibility to urethan-induced pulmonary adenomas between A/J and C57BL/6J mice: use of AXB and BXA recombinant inbred lines indicating a three-locus genetic model.

Journal of the National Cancer Institute, 1985
For insight into the number of genes governing differential susceptibility such as in mice of the inbred strain A/J (A) highly susceptible to the induction of pulmonary adenomas by urethan in comparison to resistant strain C57BL/6J (B6) mice, tumor ...
A. Malkinson, M. Nesbitt, E. Skamene
semanticscholar   +1 more source

Characterization of cortical spindles in DBA/2 and C57BL/6 inbred mice

Brain Research Bulletin, 1984
Continuous twenty-four hour EEG recordings were conducted on freely-moving DBA/2 and C57BL/6 inbred mice. No brief spindle episodes (BSEs: 6-7 cps, 1-5 sec duration, high amplitude spindle bursts) were seen in the waking EEG of C57BL/6 mice. BSEs were a conspicuous element of the EEG during active waking (AW) and quiet waking (QW) in DBA/2 mice.
openaire   +3 more sources