Results 181 to 190 of about 1,160,575 (212)
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DEXAMETHASONE INFLUENCE ON MORPHINE-INDUCED ANALGESIA IN OUTBRED SWISS AND IN INBRED DBA/2J AND C57BL/6 MICE.

Clinical Neuropharmacology, 1992
1. The influence of dexamethasone on morphine analgesia in three different strains of mice (Swiss, DBA/2J and C57BL/6) was studied by using the tail flick test. 2. I.c.v. as well as i.p. injections of dexamethasone did not modify nociceptive response in all strains. 3. I.c.v.
A, Capasso   +4 more
openaire   +2 more sources

Behavioral sensitization to drug stimulant effects in C57BL/6J and DBA/2J inbred mice.

Behavioral Neuroscience, 1994
Common features shared by addictive drugs have been difficult to identify. One ubiquitous effect of these drugs is psychomotor stimulation. Further, repeated exposure commonly results in sensitization to drug stimulant effects. This study evaluates sensitization to drugs from several drug classes in C57BL/6J and DBA/2J inbred strain mice.
T J, Phillips   +2 more
openaire   +2 more sources

A major influence of sex-specific loci on alcohol preference in C57Bl/6 and DBA/2 inbred mice

Mammalian Genome, 1998
C57Bl/6 mice reproducibly prefer to ingest more 10% ethanol in a two-bottle choice paradigm than do DBA/2J mice. In this paper we report the identification of two new sex-specific alcohol preference (Alcp) loci. Melo and associates (1996) identified two loci: Alcp1, a male-specific locus on Chromosome (Chr) 2, and Alcp2, a female- and cross-specific ...
J L, Peirce   +4 more
openaire   +2 more sources

Locomotor stimulant effects of cocaine and novel cocaine analogs in DBA/2J and C57BL/6J inbred mice

Pharmacology Biochemistry and Behavior, 1995
The current study compared the potencies of cocaine and a series of substituted phenyltropane analogs of cocaine in stimulating locomotor activity in two genetically distinct strains of mice previously shown to differ in their locomotor responsiveness to cocaine.
B K, Tolliver, J M, Carney
openaire   +2 more sources

A comparison of the discriminative stimulus properties of the atypical antipsychotic drug clozapine in DBA/2 and C57BL/6 inbred mice

Behavioural Pharmacology, 2008
Inbred mouse strain comparisons are an important aspect of pharmacogenetic research, especially in strains known to differ in regard to specific neurotransmitter systems. DBA/2 mice differ from C57BL/6 mice in terms of both functional and anatomical characteristics of dopamine systems.
Joseph H, Porter   +4 more
openaire   +2 more sources

The differences shown by C57BL/6 and DBA/2 inbred mice in detecting spatial novelty are subserved by a different hippocampal and parietal cortex interplay

Behavioural Brain Research, 1996
Inbred C57BL/6 (C57) and DBA/2 (DBA) mice with hippocampus, posterior parietal cortex or sham lesions were placed in an open-field containing five objects and their reactivity to the displacement (spatial novelty) or the substitution (object novelty) of some of these objects was examined.
ClĂ©lia Rossi-Arnaud   +2 more
exaly   +5 more sources

Quantitative Trait Loci (QTL) analysis of longevity in C57BL/6J by DBA/2J (BXD) recombinant inbred mice

Aging Clinical and Experimental Research, 2010
Genes associated with longevity have been identified using both single gene and genome-wide approaches in a variety of species. The aim of this study was to identify quantitative trait loci (QTLs) that influence longevity in male and female mice from twenty-three C57BL/6J by DBA/2J (BXD) recombinant inbred (RI) strains.Approximately 12 animals of each ...
Dean H, Lang   +8 more
openaire   +2 more sources

Role of the anterior and posterior Paraventricular Nucleus of the Thalamus on Sign-Tracking in inbred C57BL/6J and DBA/2J mice

2022
Aims: Sign-tracking (ST) behavior is a model of overwhelming attraction to rewards-associated stimuli due to incentive salience attribution as measured by the Pavlovian Conditioned Approach (PCA) paradigm. Previous studies suggested different strain-specific neurobiological substrates underlying ST behavior.
Valeria Tarmati   +2 more
openaire   +2 more sources

Role of endogenous enkephalins in locomotion and nociception studied with peptidase inhibitors in two inbred strains of mice (C57BL/6J AND DBA/2J)

Neuropharmacology, 1989
Acetorphan, a parenterally active enkephalinase inhibitor, induced dose-dependently a naloxone-reversible analgesia on the hot-plate jump test in DBA/2J (DBA2) mice but was devoid of effects in C57BL/6J (C57) mice. By contrast, acetorphan increased locomotion in both strains; however, the DBA2 strain was much more sensitive than C57 mice to the ...
Nathalie Dourmap   +2 more
exaly   +3 more sources

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