Regeneration of Soft Tissues Is Promoted by MMP1 Treatment after Digit Amputation in Mice [PDF]
, 2013 The ratio of matrix metalloproteinases (MMPs) to the tissue inhibitors of metalloproteinases (TIMPs) in wounded tissues strictly control the protease activity of MMPs, and therefore regulate the progress of wound closure, tissue regeneration and scar ...
A Kumar +65 more
core +12 more sources
Preclinical Animal Modeling in Medicine [PDF]
, 2022 The results of preclinical animal research have been successfully implemented in various medical and biological practices. The use of animals in medicine is based on significant anatomical, physiological, and molecular similarities between humans and ...
core +1 more source
Heartbreak hotel: a convergence in cardiac regeneration [PDF]
, 2016 In February 2016, the Company of Biologists hosted an intimate gathering of leading international researchers at the forefront of experimental cardiovascular regeneration, with its emphasis on ‘Transdifferentiation and Tissue Plasticity in Cardiovascular
Schneider, MD
core +1 more source
Effect of host sex and sex hormones on muscle-derived stem cell-mediated bone formation and defect healing [PDF]
, 2012 Muscle-derived stem cells (MDSCs) are known to exhibit sexual dimorphism, by donor sex, of osteogenic, chondrogenic, and myogenic differentiation potential in vitro.
Cooper, GM +3 more
core +1 more source
Motor and behavioural abnormalities associated with persistent spontaneous epilepsy in the fvb/n mouse strain [PDF]
, 2010 The FVB/N mouse strain (Mus musculus) is often used for generation of transgenic animals. However, it has also been the object of several studies in epilepsy research due to its increased susceptibility to develop spontaneous and induced seizures and its
Fernandes, Anabela Silva +3 more
core +3 more sources
Gonad-related factors promote muscle performance gain during postnatal development in male and female mice [PDF]
, 2017 To better define the role of male and female gonad-related factors (MGRF, presumably testosterone, and FGRF, presumably estradiol, respectively) on mouse hindlimb skeletal muscle contractile performance/function gain during postnatal development, we ...
Amalia Stantzou +10 more
core +3 more sources
Neuronal glucose transporter isoform 3 deficient mice demonstrate features of autism spectrum disorders. [PDF]
, 2010 Neuronal glucose transporter (GLUT) isoform 3 deficiency in null heterozygous mice led to abnormal spatial learning and working memory but normal acquisition and retrieval during contextual conditioning, abnormal cognitive flexibility with intact gross ...
Devaskar, SU +8 more
core +2 more sources
Aerobic Exercise and Pharmacological Treatments Counteract Cachexia by Modulating Autophagy in Colon Cancer [PDF]
, 2016 Recent studies have correlated physical activity with a better prognosis in cachectic patients, although the underlying mechanisms are not yet understood.
Adamo, S. +17 more
core +6 more sources
Novel individualized power training protocol preserves physical function in adult and older mice [PDF]
, 2019 Sarcopenia, the age-related loss of muscle mass and strength, contributes to frailty, functional decline, and reduced quality of life in older adults. Exercise is a recognized therapy for sarcopenia and muscle dysfunction, though not a cure. Muscle power
Fandrey, Katie R. +2 more
core +1 more source
Functional muscle hypertrophy by increased insulin-like growth factor 1 does not require dysferlin. [PDF]
, 2019 IntroductionDysferlin loss-of-function mutations cause muscular dystrophy, accompanied by impaired membrane repair and muscle weakness. Growth promoting strategies including insulin-like growth factor 1 (IGF-1) could provide benefit but may cause ...
Barton, Elisabeth R +9 more
core +1 more source