Results 111 to 120 of about 2,313,243 (300)
Antioxidant properties of HDL in transgenic mice overexpressing human apolipoprotein A-II
Journal of Lipid Research, 2002 Transgenic mice overexpressing human apolipoprotein A-II (huapoA-II) display high VLDL and low HDL levels. To evaluate the antioxidant potential of huapoA-II enriched HDL, we measured the activities of paraoxonase (PON) and platelet-activating factor ...
Elisabeth Boisfer +6 more
doaj
PLoS ONE, 2014 BackgroundWhile the immune pathogenesis caused by hepatitis B virus (HBV) infection has been studied extensively, little is known about direct pathogenic effects of HBV surface proteins.
Yuri Churin +14 more
doaj +1 more source
Advanced Materials, EarlyView.Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll +16 more
wiley +1 more source
Flexible 3D Kirigami Probes for In Vitro and In Vivo Neural Applications
Advanced Materials, EarlyView.A customizable and scalable approach to fabricate flexible 3D kirigami microelectrode arrays (MEAs) featuring up to 128 shanks, including surface and penetrating electrodes designed to interact with the 3D space of neural tissue, is presented. The 3D kirigami MEAs are successfully deployed in several neural applications, both in vitro and in vivo, and ...
Marie Jung +10 more
wiley +1 more source
Alzheimer’s Research & Therapy, 2018 Background Alzheimer’s disease (AD) is a devastating neurodegenerative disorder bearing multiple pathological hallmarks suggestive of complex cellular/molecular interplay during pathogenesis.
Feng-Qin Zhou +6 more
doaj +1 more source
Neuronal networks with coupling through amyloid beta: towards a theory for Alzheimer's disease [PDF]
arXiv, 2010 Alzheimer's disease (AD) is a common form of dementia observed in the elderly due to neurodegenerative disorder and dysfunction. This arises from alterations in synaptic functioning of neurons leading to cognitive impairment and memory loss. Recent experimental studies indicate that the amyloid beta (A beta) protein, in its dimer and oligomer forms ...
arxiv
Materials Advances in Devices for Heart Disease Interventions
Advanced Materials, EarlyView.This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra +11 more
wiley +1 more source
Human apoE3 but not apoE4 rescues impaired astrocyte activation in apoE null mice
Neurobiology of Disease, 2003 The allele E4 of apolipoprotein E (apoE) is an important risk factor for Alzheimer’s disease (AD) and the chronic brain inflammation which is associated with AD is more pronounced in subjects who carry this allele.
Gal Ophir +6 more
doaj
Neural Regeneration Research, 2016 Because of a lack of sensitive biomarkers, the diagnosis of Alzheimer′s disease (AD) cannot be made prior to symptom manifestation. Therefore, it is crucial to identify novel biomarkers for the presymptomatic diagnosis of AD.
Lan Li +10 more
doaj +1 more source
Mice transgenic for human CTLA4-CD28 fusion gene show proliferation and transformation of ATLL-like and AITL-like T cells. [PDF]
Oncoimmunology, 2022 Lee GJ +5 more
europepmc +1 more source