Results 71 to 80 of about 2,313,243 (300)
Missing Value Estimation using Clustering and Deep Learning within Multiple Imputation Framework [PDF]
arXiv, 2022 Missing values in tabular data restrict the use and performance of machine learning, requiring the imputation of missing values. The most popular imputation algorithm is arguably multiple imputations using chains of equations (MICE), which estimates missing values from linear conditioning on observed values.
arxiv
Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo.
Developmental Biology, 2001 Endocardial cells are thought to contribute at least in part to the formation of the endocardial cushion mesenchyme. Here, we created Tie2-Cre transgenic mice, in which expression of Cre recombinase is driven by an endothelial-specific promoter/enhancer.
Y. Kisanuki +5 more
semanticscholar +1 more source
Cryo-EM structures of Tau filaments from the brains of mice transgenic for human mutant P301S Tau [PDF]
Acta Neuropathol Commun, 2023 Schweighauser M +6 more
europepmc +2 more sources
N17 Modifies mutant Huntingtin nuclear pathogenesis and severity of disease in HD BAC transgenic mice. [PDF]
, 2015 The nucleus is a critical subcellular compartment for the pathogenesis of polyglutamine disorders, including Huntington's disease (HD). Recent studies suggest the first 17-amino-acid domain (N17) of mutant huntingtin (mHTT) mediates its nuclear exclusion
Barth, Albert M +13 more
core +1 more source
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
Chronic, cortex-wide imaging of specific cell populations during behavior [PDF]
arXiv, 2020 Measurements of neuronal activity across brain areas are important for understanding the neural correlates of cognitive and motor processes like attention, decision-making, and action selection. However, techniques that allow cellular resolution measurements are expensive and require a high degree of technical expertise, which limits their broad use ...
arxiv
The design of the time-of-flight system for MICE [PDF]
J.Phys.Conf.Ser.110:092004,2008, 2007 The international Muon Ionization Cooling Experiment (MICE) will carry out a systematic investigation of ionization cooling of a muon beam. As the emittance measurement will be done on a particle-by-particle basis, a sophisticated beam instrumentation is needed to measure particle coordinates and timing vs RF.
arxiv +1 more source
FEBS Open Bio, EarlyView.Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui +15 more
wiley +1 more source
Journal of Integrative Agriculture, 2016 Myostatin, a member of the transforming growth factor beta (TGF-β) superfamily, is a dominant inhibitor that acts to limit skeletal muscle growth and development.
Li-li QIAN +8 more
doaj
BMC Genomics, 2009 Background Gastric cancers are generally classified into better differentiated intestinal-type tumor and poorly differentiated diffuse-type one according to Lauren's histological categorization.
Oshima Masanobu +3 more
doaj +1 more source