Results 261 to 270 of about 4,772,082 (338)

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

ST8Sia6 overexpression protects pancreatic β cells from spontaneous autoimmune diabetes in nonobese diabetic mice. [PDF]

J Clin Invest
Choe J, Belmonte P, Crotts S, Nguyen T, Friedman D, Zastrow A, Rajcula M, Hammer B, Wilhelm C, Shapiro MJ, Matveyenko A, Shapiro VS.   +11 more
europepmc   +1 more source

A New Strain of Mice with a High Incidence of Mammary Cancers and Enlargement of the Pituitary

, 1956
Marianne Bielschowsky, F Bielschowsky, Diana Lindsay   +2 more
openalex   +1 more source

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

FEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura, Kota Shoji, Michidai Nobe, Moe Ishikawa, Miu Tanaka, Akiko Okayama, Souichi Adachi, Hidemasa Matsuo   +7 more
wiley   +1 more source

p75NTR modulation prevents cellular, cortical activity and cognitive dysfunctions caused by perinatal hypoxia. [PDF]

Brain
Chattopadhyaya B, Lee KKY, Carreño-Muñoz MI, Paris-Rubianes A, Lavertu-Jolin M, Berryer MH, Longo FM, Di Cristo G.   +7 more
europepmc   +1 more source

Fixel‐Based Analysis of Diffusion Imaging as a Quantitative Marker of Disease State in Spinocerebellar Ataxia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCAs) are a group of genetically heterogeneous neurodegenerative diseases causing progressive deterioration and reduced quality of life. Therapeutic advances have been limited by a lack of sensitive anatomic, functional, or diffusion imaging‐based biomarkers.
David J. Arpin, S. H. Subramony, the READISCA Consortium, David E. Vaillancourt, Tetsuo Ashizawa, Alexandra Durr, Thomas Mareci, Thomas Klockgether, Jennifer Faber, Henry L. Paulson, Gülin Öz, Matthew R. Burns   +11 more
wiley   +1 more source

Fixation method influences FLASH skin sparing in an in vivo leg model. [PDF]

Acta Oncol
Kristensen L, Overgaard C, Johansen J, Hansen A, Bassler N, Poulsen P, Sørensen B.   +6 more
europepmc   +1 more source