Results 321 to 330 of about 6,887,725 (399)

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann   +6 more
wiley   +1 more source

Immune cell uptake of glycinated nanoparticles conjugated to anti-fibrotic peptides enables their prolonged activity and oral administration. [PDF]

open access: yesJ Biomed Sci
Somanader-Livera DVN   +9 more
europepmc   +1 more source

Disruption of CD91 association with AXL and Fgr abrogates HSP-mediated signaling and cancer immunosurveillance. [PDF]

open access: yesOncoimmunology
Harkness T   +6 more
europepmc   +1 more source

Tppp3 determines basal body positioning and identity of respiratory cilia via microtubule assembly and sphingolipid homeostasis. [PDF]

open access: yesProc Natl Acad Sci U S A
Sakai T   +28 more
europepmc   +1 more source

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