Results 41 to 50 of about 3,757,344 (237)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Junctional adhesion molecule (JAM)-C deficient C57BL/6 mice develop a severe hydrocephalus [PDF]

, 2012
The junctional adhesion molecule (JAM)-C is a widely expressed adhesion molecule regulating cell adhesion, cell polarity and inflammation. JAM-C expression and function in the central nervous system (CNS) has been poorly characterized to date.
Michel Mittelbronn, Imhof, Beat A., Aurrand-Lions, Michel, Michel Aurrand-Lions, Deutsch, Urban, Karl H Plate, Adams, Ralf H, Liebner, Stefan, Schäfer, Julia, Enzmann, Gaby, Plate, Karl H, Urban Deutsch, Beat A Imhof, Adams, Ralf Heinrich, Mittelbronn, Michel, Imhof, Beat, Mittelbronn, Michel Guy André, Plate, Karl, Gaby Enzmann, Ralf H Adams, Engelhardt, Britta, Britta Engelhardt, Lena Wyss, Stefan Liebner, Plate, Karl H., Julia Schäfer, Wyss, Lena, Adams, Ralf H.   +27 more
core   +3 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Mechanical Recycling of Disposable Protective Masks [PDF]

Kemija u Industriji
Disposable protective face masks, the most used personal protective tools during the Covid-19 pandemic, have become a serious environmental concern that needs urgent attention.
Petra Brajković, Miće Jakić, Sanja Perinović Jozić, Ladislav Vrsalović   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Studying the principles of sustainable tourism development in Karabakh [PDF]

BIO Web of Conferences
This article explores the fundamentals of the sustainable development concept, where the dominant factor is the creation of harmony in the functioning of the nature-society system.
Khusainova Irada, Gasimova Afet Ayat, Mammadova Ilaha Isa, Yekimov Sergey, Tahirzade Jamala Fizuli, Khalilova Ramida Farrukh, Sobirov Bobur   +6 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Embodied Cognition in Performers of Large Acoustic Instruments as a Method of Designing New Large Digital Musical Instruments [PDF]

, 2019
We present The Large Instrument Performers Study, an interview-based exploration into how large scale acoustic instrument performers navigate the instrument's size-related aesthetic features during the performance.
Mice, L, Mcpherson, AP, Computer Music Multidisciplinary Research   +2 more
core   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source