Results 21 to 30 of about 136,276 (189)
Pazopanib for renal cell carcinoma leads to elevated mean arterial pressures in a murine model
Background: In the setting of metastatic RCC (mRCC), pazopanib is approved as first line therapy. Unfortunately treatment may lead to cardiotoxicity such as hypertension, heart failure, and myocardial ischemia.
Amber Kempton +7 more
doaj +1 more source
Activation of the Listeria monocytogenes Virulence Program by a Reducing Environment. [PDF]
Upon entry into the host cell cytosol, the facultative intracellular pathogen Listeria monocytogenes coordinates the expression of numerous essential virulence factors by allosteric binding of glutathione (GSH) to the Crp-Fnr family transcriptional ...
Aaron T. Whiteley +5 more
core +2 more sources
Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association
Background: The American Heart Association, in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking,
C. Tsao +39 more
semanticscholar +1 more source
Fairness in Criminal Justice Risk Assessments: The State of the Art [PDF]
Objectives: Discussions of fairness in criminal justice risk assessments typically lack conceptual precision. Rhetoric too often substitutes for careful analysis.
R. Berk +4 more
semanticscholar +1 more source
Nest success and nest site selection of wetland birds in a restored wetland system
Although most emergent wetlands across central North America have been destroyed or degraded, wetland restoration in recent decades has provided new habitat resources for wetland birds in agriculturally dominated landscapes.
Auriel M. V. Fournier +16 more
doaj
2008 Men\u27s Track and Field Statistics, George Fox ...
Gabriela Peretti Wagner (543155) +5 more
core +8 more sources
Progressive genome-wide introgression in agricultural Campylobacter coli
Hybridization between distantly related organisms can facilitate rapid adaptation to novel environments, but is potentially constrained by epistatic fitness interactions among cell components. The zoonotic pathogens Campylobacter coli and C.
S. Sheppard +23 more
semanticscholar +1 more source
Purpose Prospective treatments for age-related macular degeneration and inherited retinal degenerations are commonly evaluated in the Royal College of Surgeons (RCS) rat before translation into clinical application.
R. Ryals +7 more
semanticscholar +1 more source
A gastric resident drug delivery system for prolonged gram-level dosing of tuberculosis treatment
A retrievable device, compatible with nasogastric tube administration, releases grams of drug over weeks while residing in the stomach. Dependable drug delivery Although Mycobacterium tuberculosis (TB) infections are effectively treated with antibiotics,
Malvika Verma +48 more
semanticscholar +1 more source

