Results 81 to 90 of about 9,761,251 (311)

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad   +22 more
wiley   +1 more source

Investigations towards the stereoselective organocatalyzed Michael addition of dimethyl malonate to a racemic nitroalkene: possible route to the 4-methylpregabalin core structure

open access: yesBeilstein Journal of Organic Chemistry, 2018
Chiral derivatives of γ-aminobutyric acid are widely used as medicines and can be obtained by organocatalytic Michael additions. We show here the stereoselective synthesis of 4-methylpregabalin stereoisomers using a Michael addition of dimethyl malonate ...
Denisa Vargová   +2 more
doaj   +1 more source

5-[3-(4-Bromophenyl)-1-(2,5-dimethoxyphenyl)-3-oxopropyl]-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-tri-one

open access: yesMolbank, 2018
The title compound was prepared by a two-step reaction. The first step was the formation of a chalcone derivative using Claisen–Schmidt condensation, which was followed by the Michael addition of the formed chalcone with 1,3-dimethylbarbituric acid.
Hery Suwito   +3 more
doaj   +1 more source

Michael Terry and a group of people with the expedition's Morris Commercial truck, Western Australia?, 1928 /

open access: yes, 1928
Title devised by cataloguer from accompanying information.; Part of the: Michael Terry collection of negatives of his expeditions and travels, 1918-1971.; Michael Terry is second from right.; Also available online at: http://nla.gov.au/nla.pic ...
Terry, Michael 1899-1981, photographer.
core  

Catalyst-free and solvent-free Michael addition of 1,3-dicarbonyl compounds to nitroalkenes by a grinding method

open access: yesBeilstein Journal of Organic Chemistry, 2012
An environmentally benign, fast and convenient protocol has been developed for the Michael addition of 1,3-dicarbonyl compounds to β-nitroalkenes in good to excellent yields by a grinding method under catalyst- and solvent-free conditions.
Zong-Bo Xie   +5 more
doaj   +1 more source

Michael Terry PIC/8847/8/99 /

open access: yes, 1925
Title devised by cataloguer from accompanying information.; Part of the collection: Michael Terry collection of negatives of his expeditions and travels, 1918-1971.; Condition:; Also available online at: http://nla.gov.au/nla.pic ...
Terry, Michael, 1899-1981, photographer. pht
core  

Highly Efficient and Modularly Tuned Bicyclic Organocatalyst for the Enantioselective Michael Addition of Aldehydes to Nitroalkenes

open access: yes, 2011
Highly Efficient and Modularly Tuned Bicyclic Organocatalyst for the Enantioselective Michael Addition of Aldehydes to NitroalkenesA new type of bicyclic organocatalyst has been successfully applied to the asymmetric Michael addition of aldehydes to ...
Lu, Yun-Peng   +5 more
core   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai   +13 more
wiley   +1 more source

Michael Terry PIC/8847/8/96 /

open access: yes, 1925
Title devised by cataloguer from accompanying information.; Part of the collection: Michael Terry collection of negatives of his expeditions and travels, 1918-1971.; Condition:; Also available online at: http://nla.gov.au/nla.pic ...
Terry, Michael, 1899-1981, photographer. pht
core  

Tellurium Empowered Catalysis for Enantioselective Seleno-Michael Addition Reaction [PDF]

open access: yes
The development of a new catalyst, which has not been explored before, not only provides an alternative to the existing organocatalysts but also leads to a distinct chemical reactivity.
Raviraj Ananda, Thorat   +4 more
core   +1 more source

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