Results 51 to 60 of about 5,270 (210)
Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies
Nature Communications, 2017 Lysosomal integral membrane protein-2 (LIMP-2) is a glucocerebrosidase receptor, which is linked to kidney failure and other diseases. Here the authors show that LIMP-2 is also a phospholipid receptor and present the lipid-bound structure of the LIMP-2 ...Karen S. Conrad, Ting-Wen Cheng, Daniel Ysselstein, Saskia Heybrock, Lise R. Hoth, Boris A. Chrunyk, Christopher W. am Ende, Dimitri Krainc, Michael Schwake, Paul Saftig, Shenping Liu, Xiayang Qiu, Michael D. Ehlers +12 moredoaj +1 more sourceDAS HANDWERK DES ERZÄHLENS. POETOLOGISCHE ENTWÜRFE IN UWE TIMMS ALLE MEINE GEISTER
German Life and Letters, Volume 79, Issue 2, Page 259-280, April 2026.Abstract
Uwe Timm's autobiographical story Alle meine Geister, published in 2023, describes how Timm became an author. The story unfolds through explicit and implicit reflections on the nature and art of oral and written storytelling, against the backdrop of the author's apprenticeship and self‐employment as a furrier in the late 1950s and early 1960s. Christoph Seifenerwiley +1 more sourceYear‐round rhythms: Alpine plant species modulate soil and microbial dynamics during the growing season and under the snow
Ecological Monographs, Volume 96, Issue 1, February 2026.Abstract
Soil–plant–microbe interactions are integral throughout most terrestrial ecosystems, yet the importance of plant phenology and seasonal dynamism upon these relationships remains unknown. Given the pronounced seasonality of alpine environments, we sampled eight plant species occurring in two habitats (alpine meadow and subnival zone) across ...Adam Taylor Ruka, Johannes Schweichhart, Jiří Doležal, Kateřina Čapková, Zuzana Chlumská, Rosa Paulina Calvillo‐Medina, Travis B. Meador, Nadine Praeg, Paul Illmer, Roey Angel, Klára Řeháková +10 morewiley +1 more sourceMulti-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction
Nature Communications, 2020 On the electrocardiogram, the PR interval reflects conduction from the atria to ventricles and also serves as risk indicator of cardiovascular morbidity and mortality.Ioanna Ntalla, Lu-Chen Weng, James H. Cartwright, Amelia Weber Hall, Gardar Sveinbjornsson, Nathan R. Tucker, Seung Hoan Choi, Mark D. Chaffin, Carolina Roselli, Michael R. Barnes, Borbala Mifsud, Helen R. Warren, Caroline Hayward, Jonathan Marten, James J. Cranley, Maria Pina Concas, Paolo Gasparini, Thibaud Boutin, Ivana Kolcic, Ozren Polasek, Igor Rudan, Nathalia M. Araujo, Maria Fernanda Lima-Costa, Antonio Luiz P. Ribeiro, Renan P. Souza, Eduardo Tarazona-Santos, Vilmantas Giedraitis, Erik Ingelsson, Anubha Mahajan, Andrew P. Morris, Fabiola Del Greco M, Luisa Foco, Martin Gögele, Andrew A. Hicks, James P. Cook, Lars Lind, Cecilia M. Lindgren, Johan Sundström, Christopher P. Nelson, Muhammad B. Riaz, Nilesh J. Samani, Gianfranco Sinagra, Sheila Ulivi, Mika Kähönen, Pashupati P. Mishra, Nina Mononen, Kjell Nikus, Mark J. Caulfield, Anna Dominiczak, Sandosh Padmanabhan, May E. Montasser, Jeff R. O’Connell, Kathleen Ryan, Alan R. Shuldiner, Stefanie Aeschbacher, David Conen, Lorenz Risch, Sébastien Thériault, Nina Hutri-Kähönen, Terho Lehtimäki, Leo-Pekka Lyytikäinen, Olli T. Raitakari, Catriona L. K. Barnes, Harry Campbell, Peter K. Joshi, James F. Wilson, Aaron Isaacs, Jan A. Kors, Cornelia M. van Duijn, Paul L. Huang, Vilmundur Gudnason, Tamara B. Harris, Lenore J. Launer, Albert V. Smith, Erwin P. Bottinger, Ruth J. F. Loos, Girish N. Nadkarni, Michael H. Preuss, Adolfo Correa, Hao Mei, James Wilson, Thomas Meitinger, Martina Müller-Nurasyid, Annette Peters, Melanie Waldenberger, Massimo Mangino, Timothy D. Spector, Michiel Rienstra, Yordi J. van de Vegte, Pim van der Harst, Niek Verweij, Stefan Kääb, Katharina Schramm, Moritz F. Sinner, Konstantin Strauch, Michael J. Cutler, Diane Fatkin, Barry London, Morten Olesen, Dan M. Roden, M. Benjamin Shoemaker, J. Gustav Smith, Mary L. Biggs, Joshua C. Bis, Jennifer A. Brody, Bruce M. Psaty, Kenneth Rice, Nona Sotoodehnia, Alessandro De Grandi, Christian Fuchsberger, Cristian Pattaro, Peter P. Pramstaller, Ian Ford, J. Wouter Jukema, Peter W. Macfarlane, Stella Trompet, Marcus Dörr, Stephan B. Felix, Uwe Völker, Stefan Weiss, Aki S. Havulinna, Antti Jula, Katri Sääksjärvi, Veikko Salomaa, Xiuqing Guo, Susan R. Heckbert, Henry J. Lin, Jerome I. Rotter, Kent D. Taylor, Jie Yao, Renée de Mutsert, Arie C. Maan, Dennis O. Mook-Kanamori, Raymond Noordam, Francesco Cucca, Jun Ding, Edward G. Lakatta, Yong Qian, Kirill V. Tarasov, Daniel Levy, Honghuang Lin, Christopher H. Newton-Cheh, Kathryn L. Lunetta, Alison D. Murray, David J. Porteous, Blair H. Smith, Bruno H. Stricker, André Uitterlinden, Marten E. van den Berg, Jeffrey Haessler, Rebecca D. Jackson, Charles Kooperberg, Ulrike Peters, Alexander P. Reiner, Eric A. Whitsel, Alvaro Alonso, Dan E. Arking, Eric Boerwinkle, Georg B. Ehret, Elsayed Z. Soliman, Christy L. Avery, Stephanie M. Gogarten, Kathleen F. Kerr, Cathy C. Laurie, Amanda A. Seyerle, Adrienne Stilp, Solmaz Assa, M. Abdullah Said, M. Yldau van der Ende, Pier D. Lambiase, Michele Orini, Julia Ramirez, Stefan Van Duijvenboden, David O. Arnar, Daniel F. Gudbjartsson, Hilma Holm, Patrick Sulem, Gudmar Thorleifsson, Rosa B. Thorolfsdottir, Unnur Thorsteinsdottir, Emelia J. Benjamin, Andrew Tinker, Kari Stefansson, Patrick T. Ellinor, Yalda Jamshidi, Steven A. Lubitz, Patricia B. Munroe +186 moredoaj +1 more sourceNachtsicht ins All mit dem bloßen Auge: Sag mir, wie weit die Sterne steh'n
Physik in unserer Zeit, Volume 57, Issue 1, Page 32-40, January 2026.Beim Blick in den Nachthimmel sehen wir ohne optische Hilfsmittel und abhängig von der lokalen Lichtverschmutzung viele Hundert bis maximal einige Tausend Sterne und auch einige Galaxien. Aber wie weit sind diese von uns entfernt? Und bis zu welchen maximalen Entfernungen können wir Objekte im Weltall mit dem bloßen Auge wahrnehmen?Michael Vollmerwiley +1 more sourceRegula pastoralis
Blatt 41 und 42 sind unbedrucktRegula pastoralisVorlageform des Erscheinungsvermerks am Ende: ... vigilantiq[ue] cura in vrbe Basiliensi arte impressoria perfectus: feliciter explicit. Sub anno domini. Millesimoquadringe[n]tesimosexto: die vero decimoqui[Gregor core +1 more sourceComplement factor H contributes to mortality in humans and mice with bacterial meningitis
Journal of Neuroinflammation, 2019 Background The complement system is a vital component of the inflammatory response occurring during bacterial meningitis. Blocking the complement system was shown to improve the outcome of experimental pneumococcal meningitis. Complement factor H (FH) is E. Soemirien Kasanmoentalib, Mercedes Valls Serón, Joo Yeon Engelen-Lee, Michael W. Tanck, Richard B. Pouw, Gerard van Mierlo, Diana Wouters, Matthew C. Pickering, Arie van der Ende, Taco W. Kuijpers, Matthijs C. Brouwer, Diederik van de Beek +11 moredoaj +1 more sourceS3‐Leitlinie zur Therapie der Psoriasis vulgaris, adaptiert von EuroGuiDerm – Teil 1: Therapieempfehlungen und Monitoring [PDF]
J Dtsch Dermatol GesZusammenfassung
Der vorliegende Teil 1 der Aktualisierung der S3‐Leitlinie zur Therapie der Psoriasis vulgaris umfasst die Abschnitte „Therapieempfehlungen“, „Therapieziele“ sowie die „Monitoringempfehlungen“ zu den Therapien. Die Grundlage bildet die aktuelle Cochrane‐Netzwerkmetaanalyse, deren Ergebnisse ebenfalls dargestellt werden.Nast A, Altenburg A, Augustin M, Bachmann F, Boehncke W, Cornberg M, Geerdes‐Fenge H, Häcker B, Härle P, Klaus J, Köhm M, Köllner A, Mrowietz U, Ockenfels H, Pennitz A, Philipp S, Richter T, Rosenbach T, Schaberg T, Schlaeger M, Schmid‐Ott G, Sebastian M, Thölken K, von Kiedrowski R, Willuhn U, Zeyen C. +25 moreeuropepmc +2 more sources