Results 111 to 120 of about 1,978,722 (300)
Michigan Nonprofit Employment [PDF]
, 2010 Presents data on the number of employees in Michigan's nonprofit sector, wages, and income tax revenues; distribution of nonprofit employment by location and issue area; job growth and demand for services; and competition in comparison with for ...
Stephanie Lessans Geller
core
Advanced Science, EarlyView.This study aims to evaluate the impact of the potassium channel KCNJ2 on asthma development. KCNJ2 promotes NLRP3 inflammasome activation through both Ca2+ influx and K+ efflux in airway epithelial cells, which drives allergic airway inflammation and remodeling, suggesting a promising therapeutic target for asthma.
Yachao Cui +10 more
wiley +1 more source
Advanced Science, EarlyView.The authors engineer colorectal cancer cells with reduced redundancy of UHRF1 and DNMT1, key DNA methylation maintenance factors, lowering the maintenance threshold and sensitizing cells to inhibition. They develop reporter assays driven by endogenous tumor‐suppressor gene promoters with enhanced sensitivity and dynamic range to demethylating drugs ...
Cuicui Xia +15 more
wiley +1 more source
Orthopedic Research and Reviews, 2015 Richard E Hughes,1,2 Brian R Hallstrom,1,2 Mark E Cowen,1,3 Rochelle M Igrisan,1,2 Bonita M Singal,1,3 David A Share,2,4 1Michigan Arthroplasty Registry Collaborative Quality Initiative (MARCQI), Ann Arbor, MI, USA; 2Department of Orthopaedic Surgery ...
Hughes RE +5 more
doaj
Learnable Diffusion Framework for Mouse V1 Neural Decoding
Advanced Science, EarlyView.We introduce Sensorium‐Viz, a diffusion‐based framework for reconstructing high‐fidelity visual stimuli from mouse primary visual cortex activity. By integrating a novel spatial embedding module with a Diffusion Transformer (DiT) and a synthetic‐response augmentation strategy, our model outperforms state‐of‐the‐art fMRI‐based baselines, enabling robust
Kaiwen Deng +2 more
wiley +1 more source
Advanced Science, EarlyView.Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu +11 more
wiley +1 more source
Mild Focal Cooling Decouples Dendrites to Reconfigure Cortical Output
Advanced Science, EarlyView.Mild cooling of the cortical surface selectively modulates apical dendritic excitability, plasticity, and somato‐dendritic coupling, while uncoupling these effects from basal dendrites, and reshapes apical‐driven responses in barrel cortex during whisker touch.
Meisam Habibi Matin +2 more
wiley +1 more source
Descriptive Epidemiology of Bovine Tuberculosis in Michigan (1975–2010): Lessons Learned
Veterinary Medicine International, 2011 Despite ongoing eradication efforts, bovine tuberculosis (BTB) remains a challenge in Michigan livestock and wildlife. The objectives of this study were to (1) review the epidemiology of BTB in Michigan cattle, privately owned cervids, and wildlife ...
Chika C. Okafor +4 more
doaj +1 more source
SpatialESD: Spatial Ensemble Domain Detection in Spatial Transcriptomics
Advanced Science, EarlyView.ABSTRACT Spatial transcriptomics (ST) measures gene expression while preserving spatial context within tissues. One of the key tasks in ST analysis is spatial domain detection, which remains challenging due to the complex structure of ST data and the varying performance of individual clustering methods. To address this, we propose SpatialESD, a Spatial
Hongyan Cao +11 more
wiley +1 more source
THE "ENHANCING RURAL ECONOMIES" PROJECT: CONTEXT AND PURPOSE, TECHNIQUES AND PROCEDURES, AND EXPERIENCE TO DATE [PDF]
This paper is a part of a series of reports of the activities conducted under a grant from the Fund for Rural America, U.S. Department of Agriculture.
Moser, Colletta H., Wessen, Paul D.
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