Results 91 to 100 of about 1,925,273 (264)

Flatness optimization of micro-injection moulded parts: the case of a PMMA microfluidic component [PDF]

, 2011
Micro-injection moulding (µ-IM) has attracted a lot of interest because of its potential for the production of low-cost, miniaturized parts in high-volume.
Alcock, Jeffrey R., Wilson, A., S. Marson, A. Wilson, Marson, Silvia, U. M. Attia, LUCCHETTA, GIOVANNI, D M Allen, J. R. Alcock, Lucchetta, G., A Wilson, Allen, David M., U M Attia, J R Alcock, G Lucchetta, D. M. Allen, S Marson, Attia, Usama M.   +17 more
core   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Injection moulded micro- and nanoscale textures enhance hydrophobicity without compromising microbial safety for reusable plastic packaging

Materials & Design
Reusable packaging offers a promising route to reduce the environmental impact of single-use plastic, but its safety depends on effective sanitisation and control of bioburden across multiple use cycles.
Ronan Farrell, Yvonne J. Cortese, Lionel Tenchine, Bruno Marcilly, Golnoosh Abdeali, Daniel P. Fitzpatrick, Declan M. Devine, Romina Pezzoli   +7 more
doaj   +1 more source

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

Advanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen, Yi Zhong, Laura Dangel, Sonia Youhanna, Reza Zandi Shafagh, Jinhye Ryu, Domnica‐Gabriela Gurau, Mathias Haag, Thomas E. Mürdter, Yingxin Liang, Iro Beligiani, Nicole Ziegler, Sabine Willems, Nayere Taebnia, Wouter van der Wijngaart, Volker M. Lauschke   +15 more
wiley   +1 more source

Scaling-up of electropolishing for Ni micro-injection mould tools: Enhanced performance and throughput in microfluidic device fabrication

Advances in Industrial and Manufacturing Engineering
Precise miniature tooling is critical for the production of micro-electromechanical systems, microfluidics and micro-optics. Post-treating mould tools is critical for ensuring defect-free production in micro-injection moulding applications. In this study,
Sana Zaki, Tianyu Guan, Yuguo Zhang, Minghzi Yu, Nan Zhang, Michael D. Gilchrist   +5 more
doaj   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Micro powder injection moulding: Processes, materials and applications

, 2022
S.63-70Micro Powder Injection Moulding (MicroPIM) continues to attract attention as a unique process by which to manufacture metal and ceramic micro components in medium to high volumes.
Moritz, Tassilo, Piotter, Volker
core   +1 more source

Soft, Multi‐Wavelength Photoplethysmography Enables Reliable Neonatal Blood Pressure Monitoring Via Error Stratification

Advanced Science, EarlyView.
A soft hybrid multi‐wavelength PPG wearable acquires neonatal signals. Synchronized PPG and invasive ABP data are segmented into fixed windows. A 1D‐EfficientNet model predicts segment‐level SBP and DBP. Model performance is examined with retrospective subgroup analysis across acquisition conditions.
Wenqi Shi, Lanlan Mi, Jiarong Chen, Biao Liu, Min Wang, Zisheng Dai, Bin Liu, Ruize Gao, Yunfeng Lin, Weiwei Guo, Guoxing Wang, Wenyi Luo, Cheng Chen   +12 more
wiley   +1 more source

Micro vs nano: influence of filler size on the rheological and mechanical properties of highly-filled PLA/HAp and PCL/HAp composites

Journal of Materials Research and Technology
This work aims to elucidate the influence of filler particle size on the rheological behaviour, as well as the micro- and macromechanical properties, of polymer-ceramic composites.
Bartłomiej Kryszak, Aleksandra Ujčić, Veronika Gajdošová, Miroslav Šlouf, Konrad Szustakiewicz   +4 more
doaj   +1 more source