Mechanoregulatory Effects of Cell‐Scale Microwells on Epithelial Cell Phenotype
Advanced Functional Materials, EarlyView.In small polycaprolactone microwells, A549 epithelial cells span well edges, in contrast to cells growing on flat substrates. Focal adhesion sites (yellow) concentrate at topographic boundaries, while cytoskeletal tension (magenta stress fibers) is transmitted to the nucleus (blue), reducing nuclear sphericity.
Ruiwen He +10 more
wiley +1 more source
Photodynamic Effects of Topical Photosensitizer, Photodithazine Using Micro-LED for Acne Bacteria Induced Inflammation. [PDF]
Ann DermatolLee SM, Kim SH, Kim Z, Lee JB.
europepmc +1 more source
Nanothermometry in Living Cells: Physical Limits, Conceptual and Material Challenges
Advanced Functional Materials, EarlyView.Heat and temperature are fundamental to life. When nanothermometers began probing regions as small as a living cell, they triggered controversial claims of large intracellular temperature gradients. We review physical constraints energy‐conservation, entropy production, thermodynamic fluctuations, and molecular dynamics.
Taras Plakhotnik
wiley +1 more source
Actuating and Sensing Composites of Liquid Crystal Elastomers and Poly(ionic liquid)s
Advanced Functional Materials, EarlyView.Ionic conductive, mechanically tough, flexible, and stretchable filaments of a composite material comprising a liquid crystal elastomer and a poly(ionic liquid) are produced through 3D printing, which exhibit large actuation strain under stimulation and electrical resistance variation in response to deformation or environmental condition changes. Their
Zeping Liu +6 more
wiley +1 more source
Design considerations for optogenetic applications of soft micro-LED-based device systems across diverse nervous systems. [PDF]
Bioact MaterLee JY +6 more
europepmc +1 more source
Advanced Functional Materials, EarlyView.xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat +11 more
wiley +1 more source
Advancing LED technology: the FDCSP element's breakthrough in mini and micro-LED packaging and backlight module enhancement. [PDF]
Discov NanoChen JH +5 more
europepmc +1 more source
Advanced Functional Materials, EarlyView.Bioprosthetic aortic valves have revolutionized the treatment of aortic stenosis, but their durability is limited by structural valve deterioration (SVD). This review focuses on the pericardial tissue at the heart of these valves, examining how its mechanical properties and calcification drive fatigue and failure.
Gabriele Greco +7 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Nanosecond pulse laser texturing yields superhydrophobic and superhydrophilic AA2024 surfaces. Salt‐spray tests show that periodic superhydrophobic patterns suppress pitting, whereas superhydrophilic textures enhance it, linking laser‐induced morphology, wettability, and oxide chemistry to corrosion resistance.
Lis Geraldine Zschach +8 more
wiley +1 more source
Author Correction: A micro-LED array based platform for spatio-temporal optogenetic control of various cardiac models. [PDF]
Sci RepJunge S +10 more
europepmc +1 more source