Results 41 to 50 of about 1,937,372 (315)

Optimizing Overcut Parameter of Micro-Holes Machining by EDM Using Taguchi Method [PDF]

Engineering and Technology Journal, 2014
In this paper Taguchi method was performed to estimate the optimum overcut parameter for Electro Discharge Machining (EDM) to obtain micro-holes of copper alloy workpieces.
Laith A. Mohammed, Shukry H. Aghdeab
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Comparative Study on Micro and Nano Sized SiC Particulates Reinforced Al7075 Composites using Stir Casting Process [PDF]

Archives of Metallurgy and Materials
This paper is designed to investigate the wear and mechanical characterization of metal matrix composites (MMCs) by using micro and nano SiC on Al to study the influence of micro/nano SiC on the properties of fabiricated composite.
M. Ravikumar, H.N. Reddappa, R. Suresh, E.R. Babu, C. Reddy Nagaraja   +4 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Empirical development taxanomy of micro, small and medium-sized enterprises in South Moravian Region

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2013
This paper represents a pilot study examining entrepreneurial behavior patterns within the area of development of micro, small and medium-sized market active enterprises in South Moravian Region from the perspective of strategic management.
Veronika Bumberová, Vojtěch Koráb
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

User Consent in MOOCs – Micro, Meso, and Macro Perspectives

International Review of Research in Open and Distributed Learning, 2018
While many strategies for protecting personal privacy rely on regulatory frameworks, consent, and anonymizing data, they are not always effective. Terms and Conditions often lag behind advances in technology, software, and user behaviours, and consent to
Mohammad Khalil, Paul Prinsloo, Sharon Slade   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Estimating Factors Affecting Technical Efficiency in Indian Manufacturing Sector [PDF]

Eurasian Journal of Business and Economics, 2019
Existing studies could not estimate the technical efficiency (TE) of firms and it’s affecting factors in the Indian manufacturing sector. So, the present study examines the TE of firms using a stochastic frontier production function approach.
Ajay Kumar SINGH, Shah Nawaz ASHRAF, Ashish ARYA   +2 more
doaj   +1 more source

The Micro Design of Micro-Lecture [PDF]

Advances in Computer Science Research, 2015
This paper on the introduction of the concept, significance and application of Micro-Lecture model, based on the proposed micro course design should stick to flip the classroom education connotation and the characteristics of micro class resources, fully grasp and use micro class design series micro strategies, including: micro perspective of topic ...
openaire   +1 more source