Results 21 to 30 of about 327,349 (219)
Implantable electronic tags are crucial for the conservation of marine biodiversity. However, the power supply associated with these tags remains a significant challenge.
Bo Liu +12 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Performance Optimization of CsPb(I1–xBrx)3 Inorganic Perovskite Solar Cells with Gradient Bandgap
In recent years, inorganic perovskite solar cells (PSCs) based on CsPbI3 have made significant progress in stability compared to hybrid organic–inorganic PSCs by substituting the volatile organic component with Cs cations.
Luning Wang +6 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Development of a Rolling-Mode Wave Energy Converter for Powering Marine Monitoring Nodes
To address the energy supply demands of the distributed marine monitoring nodes, developing marine sustainable energy sources has become imperative. This study develops a rolling-mode direct wave energy converter, with a series of dynamic simulations and
Mingli Fan +6 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Highlights The tautomeric UV absorbers (UV320/UV327) in perovskites reveal keto–enol tautomerism, generating extra –C=O groups to enhance defect passivation.
Yong Wang +12 more
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Hız Kesiciden Elektrik Enerjisi Üretimi
Bu çalışmada, araç hızını yavaşlatmak için kullanılan hız kesiciden yararlanarak alternatif enerji kaynağı tasarlanmıştır. Özel hız kesici tasarımı ile hidrolik sistem birleştirilmiş ve mekanik enerji üretilmiştir.
Ali Demircan +2 more
doaj

