Results 81 to 90 of about 1,925,224 (223)

Flatness optimization of micro-injection moulded parts: the case of a PMMA microfluidic component [PDF]

, 2011
Micro-injection moulding (µ-IM) has attracted a lot of interest because of its potential for the production of low-cost, miniaturized parts in high-volume.
Alcock, Jeffrey R., Wilson, A., S. Marson, A. Wilson, Marson, Silvia, U. M. Attia, LUCCHETTA, GIOVANNI, D M Allen, J. R. Alcock, Lucchetta, G., A Wilson, Allen, David M., U M Attia, J R Alcock, G Lucchetta, D. M. Allen, S Marson, Attia, Usama M.   +17 more
core   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Ultrashort Pulsed Laser Fabrication of High-Performance Polymer-Film-Based Moulds for Rapid Prototyping of Microfluidic Devices

Journal of Manufacturing and Materials Processing
Microfluidic device prototyping demands rapid, cost-effective, and high-precision mould fabrication, yet ultrashort pulsed laser structuring of polymer inserts remains underexplored.
Pieter Daniël Haasbroek, Mischa Wälty, Michael Grob, Per Magnus Kristiansen   +3 more
doaj   +1 more source

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

Advanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen, Yi Zhong, Laura Dangel, Sonia Youhanna, Reza Zandi Shafagh, Jinhye Ryu, Domnica‐Gabriela Gurau, Mathias Haag, Thomas E. Mürdter, Yingxin Liang, Iro Beligiani, Nicole Ziegler, Sabine Willems, Nayere Taebnia, Wouter van der Wijngaart, Volker M. Lauschke   +15 more
wiley   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Injection moulded micro- and nanoscale textures enhance hydrophobicity without compromising microbial safety for reusable plastic packaging

Materials & Design
Reusable packaging offers a promising route to reduce the environmental impact of single-use plastic, but its safety depends on effective sanitisation and control of bioburden across multiple use cycles.
Ronan Farrell, Yvonne J. Cortese, Lionel Tenchine, Bruno Marcilly, Golnoosh Abdeali, Daniel P. Fitzpatrick, Declan M. Devine, Romina Pezzoli   +7 more
doaj   +1 more source

Soft, Multi‐Wavelength Photoplethysmography Enables Reliable Neonatal Blood Pressure Monitoring Via Error Stratification

Advanced Science, EarlyView.
A soft hybrid multi‐wavelength PPG wearable acquires neonatal signals. Synchronized PPG and invasive ABP data are segmented into fixed windows. A 1D‐EfficientNet model predicts segment‐level SBP and DBP. Model performance is examined with retrospective subgroup analysis across acquisition conditions.
Wenqi Shi, Lanlan Mi, Jiarong Chen, Biao Liu, Min Wang, Zisheng Dai, Bin Liu, Ruize Gao, Yunfeng Lin, Weiwei Guo, Guoxing Wang, Wenyi Luo, Cheng Chen   +12 more
wiley   +1 more source

Scaling-up of electropolishing for Ni micro-injection mould tools: Enhanced performance and throughput in microfluidic device fabrication

Advances in Industrial and Manufacturing Engineering
Precise miniature tooling is critical for the production of micro-electromechanical systems, microfluidics and micro-optics. Post-treating mould tools is critical for ensuring defect-free production in micro-injection moulding applications. In this study,
Sana Zaki, Tianyu Guan, Yuguo Zhang, Minghzi Yu, Nan Zhang, Michael D. Gilchrist   +5 more
doaj   +1 more source

Micro powder injection moulding: Processes, materials and applications

, 2022
S.63-70Micro Powder Injection Moulding (MicroPIM) continues to attract attention as a unique process by which to manufacture metal and ceramic micro components in medium to high volumes.
Moritz, Tassilo, Piotter, Volker
core   +1 more source

Beyond Traditional Phenolics: Disulfide Bonds for Performance Enhancement of Aerospace Ablation‐Resistant Materials from Processing to Recycling

Advanced Science, EarlyView.
The dynamic disulfide bonds facilitated the development of high‐performance aerospace ablation‐resistant materials. At moderate temperature, the dissociation and recombination of disulfide bonds ensured excellent processability, mechanical properties, and recycling ability of phenolic resin; at high temperature, cleavage of disulfide bonds produced ...
Yu Li, Boyuan Hu, Xiaolong Xing, Huan Yang, Ziqi Zhang, Cheng Bian, Ruixue Bai, Ling Yue, Chengshuang Zhang, Xinli Jing   +9 more
wiley   +1 more source