Results 71 to 80 of about 55,084 (278)

Developments in albuminuria testing: A key biomarker for detection, prognosis and surveillance of kidney and cardiovascular disease—A practical update for clinicians

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Albuminuria, the abnormal presence of albumin in urine, is a key marker of kidney damage and a strong predictor of kidney and cardiovascular outcomes. Its clinical significance has evolved from early historical observations to its current role in chronic kidney disease (CKD) detection, risk stratification and treatment monitoring.
Jelle M. Beernink, Dominique van Mil, Gozewijn D. Laverman, Hiddo J. L. Heerspink, Ron T. Gansevoort   +4 more
wiley   +1 more source

The impact of insulin pump therapy compared to multiple daily injections on complications and mortality in type 1 diabetes: A real‐world retrospective cohort study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Clinical trials have demonstrated the benefits of insulin pump therapy compared with multiple daily injections (MDI) in type 1 diabetes. However, contemporaneous real‐world data are limited. This study investigated the real‐world impact of insulin pump therapy compared with MDI. Materials and Methods A retrospective cohort study of adults
Sophie Haughton, David Riley, Simon Berry, Muhammad Fahad Arshad, Aikaterini Eleftheriadou, Matthew Anson, Yew Wen Yap, Daniel J. Cuthbertson, Rayaz A. Malik, Shazli Azmi, Uazman Alam, Ahmed Iqbal   +11 more
wiley   +1 more source

Evaluation of Glycated Albumin and Microalbuminuria as Early Risk Markers of Nephropathy in Type 2 Diabetes Mellitus [PDF]

Journal of Clinical and Diagnostic Research, 2013
Introduction: Since Glycated Albumin (GA) reflects short term variations and glycated protein shows degrees of hyperglycaemia, the objective of this study was to find GA and microalbuminuria as a early risk markers along with the duration of ...
Suresh Babu Kondaveeti, Kumaraswamy D, Shishir Mishra, Aravind Kumar R, I Anand Shaker   +4 more
doaj   +1 more source

Endothelial dysfunction and inflammation in asymptomatic proteinuria [PDF]

, 2003
Background. Proteinuria is associated with vascular risk and a systemic increase in vascular permeability. Endothelial dysfunction occurs early in atherosclerosis and modulates vascular permeability. Vascular risk and chronic inflammation are associated.
Adams, Adams, Biasucci, Blum, Casino, Celermajer, Chauveau, Clausen, Cleland, Cooke, Dietz, Doshi, Drab, Festa, Fichtlscherer, Furchgott, Fuster, Grossmann, Haaber, Haverkate, Hernandez, Jensen, Jensen, Johnston, Joles, Kannel, Khan, Khan, Koenig, Kubes, Laurent, Lewis, Lewis, Lip, Liuzzo, Ludmer, Luscher, Michel, Mogensen, Moncada, Morris, Morris, Morrow, Nabel, Noon, Noon, Pohl, Quyyumi, Rayman, Razani, Ridker, Ross, Ross, Rubanyi, Schalkwijk, Schubert, Serne, Shore, Sorensen, Stroes, Tenland, Thambyrajah, Tooke, van Guldener, Vogel, Williams, Yuan, Yudkin   +67 more
core   +1 more source

Genetic risk and polygenic risk score assessment of prediabetes and progression to type 2 diabetes

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To identify susceptibility loci to prediabetes and evaluate the performance of existing polygenic risk scores (PGS) for type 2 diabetes (T2D) in predicting prevalent prediabetes and progression to diabetes. Materials and Methods We conducted a case–control Genome‐Wide Association Study (GWAS) on Qatar Biobank (QBB) participants with ...
Usama Aliyu, Umm‐Kulthum Ismail Umlai, Nayra M. Al‐Thani, Salman M. Toor, Abdul Badi Abou‐Samra, Omar M. E. Albagha   +5 more
wiley   +1 more source

Progression of Renal Insufficiency in Patients with Essential Hypertension Treated with Renin Angiotensin Aldosterone System Blockers: An Electrocardiographic Correlation

Diseases, 2017
Background: There is a frequent association between renal insufficiency and cardiovascular disease in patients with essential hypertension (HTN). The aim of this study was to analyze the relationship between ECG parameters and the progress of renal ...
Luis Rodriguez-Padial, Finn Akerström, María G. Barderas, Fernando Vivanco, Miguel A. Arias, Julian Segura, Luis M. Ruilope   +6 more
doaj   +1 more source

Factors Associated with Remission and/or Regression of Microalbuminuria in Type 2 Diabetes Mellitus [PDF]

, 2014
The aim of this study was to clarify the factors associated with the remission and/or regression of microalbuminuria in Japanese patients with type 2 diabetes mellitus.
Hirota, Daisyo, Kataoka, Hitomi, Kodera, Ryo, Makino, Hirofumi, Miyatake, Nobuyuki, Obika, Mikako, Ogawa, Daisuke, Ono, Tetsuichiro, Shikata, Kenichi, Wada, Jun   +9 more
core   +1 more source

Association between serum uric acid levels and galectin‐3 in patients with uncomplicated type 2 diabetes

Internal Medicine Journal, EarlyView.
Abstract Background Serum uric acid (SUA) has been associated with an increased risk of cardiovascular disease (CVD) in both the general population and individuals with type 2 diabetes (T2DM). Identification of high‐risk individuals is crucial for the primary prevention of CVD.
Funda Yildirim Borazan, Ihsan Ergun, Tuba Candar, Ali Kemal Oguz   +3 more
wiley   +1 more source

Association of the IL‐6R rs2228145 polymorphism with diabetic nephropathy: A case‐control study

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Introduction The pathogenesis of diabetes mellitus (DM) and its complications has been previously linked to elevated levels of interleukin‐6 (IL‐6); IL‐6 triggers intracellular pathways through interaction with the IL‐6 receptor (IL‐6R). This study aimed to determine the association of single nucleotide polymorphisms (SNPs) IL‐6 −597G/A ...
Pavla Izakovicova, Simona Slezakova, Tereza Deissova, Hana Poskerova, Petra Borilova Linhartova, Ladislav Dusek, Katerina Kankova, Lydie Izakovicova Holla   +7 more
wiley   +1 more source

Albuminuria predicting outcome in diabetes: Incidence of microalbuminuria in Asia–Pacific Rim [PDF]

, 2004
Albuminuria predicting outcome in diabetes: Incidence of microalbuminuria in Asia–Pacific Rim. Microalbuminuria is not an unusual finding in the general population, even in individuals without diabetes, hypertension, or cardiovascular risk factors ...
Weir, Matthew R.
core   +1 more source