Results 41 to 50 of about 68,882 (316)

The role of acetylcholine neurotransmission in the pharmacotherapy of cognitive dysfunction

open access: yesОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2018
Microangiopathy and deficit in cholinergic system innervating cerebral cortex and controlling the plasticity of neuronal structuresplay an important role in the formation of cognitive disorders.
D. V. Zaharov, V. A. Mihailov
doaj   +1 more source

Peculiarities of the condition of vascular platelic hemostasis in diabetic retinopathy and diabetic nephropathy in rats

open access: yesJournal of Education, Health and Sport, 2020
The article presents experimental data on the study of changes in vascular platelet hemostasis in rats with experimental DR and DN on the background of type 2 diabetes.
I. I. Hrytsan   +3 more
doaj   +1 more source

Circulating Biomarkers to Predict Diabetic Retinopathy in Patients with Diabetic Kidney Disease

open access: yesVision, 2023
The purpose of this review is to outline the currently available circulating biomarkers to predict diabetic retinopathy (DR) in patients with diabetic kidney disease (DKD).
Jonny   +4 more
doaj   +1 more source

Topical Reappraisal of Molecular Pharmacological Approaches to Endothelial Dysfunction in Diabetes Mellitus Angiopathy

open access: yesCurrent Issues in Molecular Biology, 2022
Diabetes mellitus (DM) is a frequent medical problem, affecting more than 4% of the population in most countries. In the context of diabetes, the vascular endothelium can play a crucial pathophysiological role. If a healthy endothelium—which is a dynamic
Constantin Munteanu   +11 more
doaj   +1 more source

A rare case of renal thrombotic microangiopathy associated with Castleman’s disease [PDF]

open access: yes, 2017
BACKGROUND: Castleman’s disease (CD) is an uncommon, heterogeneous lympho-proliferative disorder leading to high circulating levels of interleukin-6 (IL-6) and vascular endothelial growth factor (VEGF).
Chen, Ying Maggie   +3 more
core   +2 more sources

Methods of Evaluation and Quantification of Microangiopathy in High Perfusion Microangiopathy (Chronic Venous Insufficiency and Diabetic Microangiopathy)

open access: bronzeJournal of Cardiovascular Pharmacology and Therapeutics, 2002
Noninvasive macro- and microcirculatory tests provide quantitative information that offers answers to most questions posed in venous diseases. Duplex scanning is used to assess the macrocirculation, and microcirculatory methods are used to assess and quantify venous microangiopathy. Laser Doppler flowmetry is used to assess perfusion.
M. T. DeSanctis   +4 more
openalex   +4 more sources

PREVALENCE AND RISK FACTORS OF ASYMPTOMATIC CEREBRAL INFARCTION

open access: yesKlinicist, 2015
Acute stroke manifesting as focal neurological deficit is a leading cause of death and disability. Of interest is the problem of asymptomatic cerebral infarctions (AСI), in which there is focal medullary involvement unaccompanied by the development of ...
R. R. Zhetishev   +3 more
doaj   +1 more source

Eculizumab is a safe and effective treatment in pediatric patients with atypical hemolytic uremic syndrome [PDF]

open access: yes, 2016
Atypical hemolytic uremic syndrome (aHUS) is caused by alternative complement pathway dysregulation, leading to systemic thrombotic microangiopathy (TMA) and severe end-organ damage.
Al-Akash, Samhar I   +14 more
core   +2 more sources

Interferon-complement loop in transplant-associated thrombotic microangiopathy.

open access: yesBlood Advances, 2020
Transplant-associated thrombotic microangiopathy (TA-TMA) is an important cause of morbidity and mortality after hematopoietic stem cell transplantation (HSCT). The complement inhibitor eculizumab improves TA-TMA, but not all patients respond to therapy,
S. Jodele   +6 more
semanticscholar   +1 more source

Pathogenesis of Thrombotic Microangiopathies [PDF]

open access: yesAnnual Review of Pathology: Mechanisms of Disease, 2007
Profound thrombocytopenia and microangiopathic hemolytic anemia characterize thrombotic microangiopathy, which includes two major disorders: thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS). TTP has at least three types: congenital or familial, idiopathic, and nonidiopathic.
X. Long Zheng, J. Evan Sadler
openaire   +3 more sources

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