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Microarray Analysis of Sarcomas
Advances in Anatomic Pathology, 2006Microarrays began to be used to study gene expression profiles in the mid-1990s, but it was only after 2000 that serious attempts have been made to apply this technology to investigate sarcomas. Microarray technologies provide a comprehensive survey of active molecular pathways and potential molecular targets for diagnosis and treatment, but are ...
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Microarray Data Analysis and Mining
2004DNA microarray is an innovative technology for obtaining information on gene function. Because it is a high-throughput method, computational tools are essential in data analysis and mining to extract the knowledge from experimental results. Filtering procedures and statistical approaches are frequently combined to identify differentially expressed ...
SAVIOZZI, Silvia +4 more
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Borrelia burgdorferi Microarray Analysis [PDF]
, 2017 Microarray studies have contributed significantly to the current understanding of Borrelia burgdorferi genome content and transcriptional regulation. Here, we describe the use of microarray technology for several aspects of B. burgdorferi genomic analysis.
Radha Iyer, Ira Schwartz
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The analysis of microarray data
Pharmacogenomics, 2003This article describes issues, techniques and algorithms for analyzing data from microarray experiments. Each such experiment generates a large amount of data, only a fraction of which comprises significant differentially expressed genes. The precise identification of these interesting genes is heavily dependent not only on the statistical data ...
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Methods for Microarray Data Analysis
2007This chapter outlines a typical workflow for micraorray data analysis. It aims at explaining the background of the methods as this is necessary for deciding upon a specific numerical method to use and for understanding and interpreting the outcomes of the analyses.
De Bruyne, Veronique +2 more
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Analysis of microRNA Microarrays in Cardiogenesis
2015microRNAs are a subclass of noncoding RNAs which have been demonstrated to play pivotal roles in multiple cellular mechanisms. microRNAs are small RNA molecules of 22-24 nt in length capable of modulating protein translation and/or RNA stability by base-priming with complementary sequences of the mRNAs, normally at the 3'untranslated region.
Francisco J. Esteban +5 more
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Lectin Microarrays for Glycoprotein Analysis
2007Glycosylation is one of the most common posttranslational modifications, with more than half of all known proteins thought to be glycoproteins. Alterations in glycosylation play a role in a diverse set of biological phenomena including tumor cell metastasis, intracellular communication, and inflammation. The complexity of glycosylation at the molecular
Kanoelani T. Pilobello, Lara K. Mahal
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DNA Content Analysis on Microarrays
2004The genome sequencing of protozoan parasites has facilitated the development of powerful postgenomics tools such as DNA microarrays and revolutionized the study of parasite biology. Large-scale genomic comparisons are useful in identifying the extent of genomic variability among related strains and isolates.
Preetam H. Shah +2 more
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Analysis of DNA Microarray Data
Current Topics in Medicinal Chemistry, 2004Recent advances in DNA microarray technology have great impact on many areas of biomedical research and pharmacogenomics: discovering novel targets and genes, elucidating signatures of complex diseases, transcriptional profiling of models for diseases, and the development of individually optimized drugs based on differential gene expression patterns ...
Hubert Hackl +4 more
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Application of ESTs in Microarray Analysis
2009Microarray analyses provide information on the relative expression levels of large numbers of gene products (transcripts). As such they have been widely used to examine differences in gene expression across a variety of samples such as tissues and life-cycle stages.
Daryl R. Williams +5 more
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