Results 41 to 50 of about 2,142,190 (311)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Impact of soil management on the functional activity of microbial communities associated to cork oak rhizosphere [PDF]
, 2007 The microbial ecology of cork oak rhizosphere was investigated using the Biolog community level physiological profile (CLPP) that provides a unique metabolic fingerprint helpful for the characterization of complex microbial communities.
Caredda, Marco +3 more
core
Microbial community changes induced by Managed Aquifer Recharge activities: linking hydrogeological and biological processes [PDF]
, 2019 Managed Aquifer Recharge (MAR) is a technique used worldwide to increase the availability of water resources. We study how MAR modifies microbial ecosystems and its implications for enhancing biodegradation processes to eventually improve groundwater ...
Barba Ferrer, Maria del Carme +6 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Journal of Food Quality and Hazards Control, 2023 Background: Fermented foods are gaining interest because of their ability to improve health, as well as their good taste, and the desire of many to eat them.
A.R.E. El-Hadary +2 more
doaj
Endolithic colonization of fluid inclusion trails in mineral grains [PDF]
, 2005 Many scenarios for the colonization of planetary surfaces by microbial life involve endoliths.
Baron, M., Cockell, C. S., Parnell, J.
core
Unravelling the active microbial community in a thermophilic anaerobic digester-microbial electrolysis cell coupled system under different conditions [PDF]
, 2017 Thermophilic anaerobic digestion (AD) of pig slurry coupled to a microbial electrolysis cell (MEC) with a recirculation loop was studied at lab-scale as a strategy to increase AD stability when submitted to organic and nitrogen overloads.
Bonmatí Blasi, August +2 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Veterinary Medicine and ScienceCitrobacter freundii is a zoonotic bacterium with special public health importance as a carrier and source of multidrug resistance (MDR) genes. Here, the prevalence, genetic heterogeneity, and antimicrobial resistance pattern of C.
Hussein Khodabandeh +4 more
doaj +1 more source