A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou +14 more
wiley +1 more source
Disruption-induced changes in syntrophic propionate and acetate oxidation: flocculation, cell proximity, and microbial activity. [PDF]
Weng N, Najafabadi HN, Westerholm M.
europepmc +1 more source
Bacterial α‐diversity decreases, but stochasticity and community stability increase across the 15 m‐depth vertical profiles and along the degraded gradient within the active layer. The abundance and interaction of core taxa mainly control community stability in the active and permafrost layers, respectively.
Shengyun Chen +13 more
wiley +1 more source
Soil Texture Mediates the Toxicity of ZnO and Fe3O4 Nanoparticles to Microbial Activity. [PDF]
Shah GM +8 more
europepmc +1 more source
A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu +6 more
wiley +1 more source
Integrating Rock Dust and Organic Amendments to Enhance Soil Quality and Microbial Activity for Sustainable Crop Production. [PDF]
Armah A +9 more
europepmc +1 more source
A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet +5 more
wiley +1 more source
Composition of soil fungal communities and microbial activity along an elevational gradient in Mt. Jiri, Republic of Korea. [PDF]
Mitcov A +7 more
europepmc +1 more source
Promoting Treg Polarization‐Mediated Anti‐Scar and Appendage Regeneration in Wound Healing
This study develops a PLGA@LA‐BMP4‐PG bilayer scaffold to address scar formation and appendage loss in skin repair. The piezoelectric PLA layer enhances cell migration via electric fields, while GelMA delivers LA promoting Tregs polarization and BMP4 inhibiting FBs differentiation.
Yiwen Yang +10 more
wiley +1 more source
The effect of broadcast struvite fertilization on element soil content and microbial activity changes in winter wheat cultivation in southwest Poland. [PDF]
Ramut R +6 more
europepmc +1 more source

