Results 101 to 110 of about 1,169,927 (232)

Highly Sensitive Spatial Host‐Microbiome Transcriptomics in FFPE Tissues via Iterative Hydrogel Expansion

open access: yesAdvanced Science, EarlyView.
Ex‐spRandom is a spatial transcriptomics platform that synergizes random‐primed chemistry with iterative hydrogel expansion. By physically decrowding the dense FFPE matrix, this scalable technology shatters the traditional resolution‐sensitivity barrier.
Shunji Zhang   +7 more
wiley   +1 more source

CroCoDeEL: accurate control-free detection of cross-sample contamination in metagenomic data

open access: yesNature Communications
Metagenomic sequencing provides insights into microbial communities, but it can be compromised by technical biases, including cross-sample contamination.
Lindsay Goulet   +7 more
doaj   +1 more source

Autologous transplant: microbial contamination of hematopoietic stem cell products

open access: yesBrazilian Journal of Infectious Diseases
Hematopoietic progenitor cells from peripheral blood (HPCPB) are commonly used for autologous and allogenic transplants in patients with most various onco-hematological diseases, and despite the utilization of sterile techniques during collection and ...
Igor Dullius Almeida   +3 more
doaj   +1 more source

Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges

open access: yesAdvanced Science, EarlyView.
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen   +6 more
wiley   +1 more source

Translational Barriers and AI‐Driven Challenges of Microfluidics‐Enabled Wearables and Implantable Systems in Personalized Medicine

open access: yesAdvanced Science, EarlyView.
An integrative review of microfluidics‐enabled wearables and implantable systems reveals a single‐track translation pipeline, bridging functional biomaterials with clinical utility. Dynamic feedback loops driven by artificial intelligence advance diagnostics toward personalized closed‐loop theranostics.
Ke Huang   +3 more
wiley   +1 more source

A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints

open access: yesAdvanced Science, EarlyView.
ARESEC is a synthetic platform that reconstructs functional V(D)J recombination in HEK293T cells. By introducing RSS elements and co‐expressing RAG1/2 and TdT across all three antibody CDRs, it enables programmable junctional diversification and direct generation of high‐affinity variants targeting PD‐1/PD‐L1, overcoming the evolutionary constraints of
Wang Liu   +3 more
wiley   +1 more source

Hygiene and safety of Irish beef carcasses. [PDF]

open access: yes, 2002
End of Project ReportInvestigations were carried out in a number of beef abattoirs in Ireland. Information was obtained on the hygienic status of the carcasses being produced and also on their safety, using the presence of Salmonella as an indicator ...
Kerr, Marie, Sheridan, James J.
core   +1 more source

Responses of soil microbes to antimony stress and coupled nutrient cycling in karst mining areas of Southwest China

open access: yesEcotoxicology and Environmental Safety
Persistent and poorly mobile heavy metals in soil present a widespread environmental challenge. Among these, antimony (Sb) is a contaminant of emerging concern whose transformation and migration in soil require further investigation to inform effective ...
Libo Pan   +7 more
doaj   +1 more source

Mesoporous PU/PEDOT:PSS Electrodes Reveal Population‐Level Stochastic Bioelectrical Dynamics in Marine Diatoms

open access: yesAdvanced Science, EarlyView.
Mesoporous mixed ionic‐electronic PU/PEDOT: PSS electrodes enable label‐free detection of stochastic extracellular bioelectrical dynamics in living Phaeodactylum tricornutum. Living diatoms actively modulate interfacial ionic dynamics, establishing stochastic electrochemical noise as a sensitive probe of microbial bioelectrochemical activity and a new ...
David M. S. Silva   +7 more
wiley   +1 more source

Evaluation of microbial content of some sunscreen creams in Iran’s market

open access: yesPharmaceutical and Biomedical Research, 2015
The risk of microbial contamination in the cosmetic products especially in smuggled preparations and transmission of it to consumers is very high. In this study, the microbial content and the pollution of some sunscreen creams in the market and one ...
Narges Sedghi Sharif-Abad   +4 more
doaj  

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