Results 311 to 320 of about 753,950 (380)

A socio-ecological System Dynamics model of antimicrobial use and resistance

open access: yes
Redman-White CJ   +4 more
europepmc   +1 more source

Drug repurposing to overcome microbial resistance

Drug Discovery Today, 2022
Infections are a growing global threat, and the number of resistant species of microbial pathogens is alarming. However, the rapid development of cross-resistant or multidrug-resistant strains and the development of so-called 'superbugs' are in stark contrast to the number of newly launched anti-infectives on the market. In this review, I summarize the
J. Jampílek
openaire   +3 more sources

Anti‐Microbial Drug Resistance: A Human Disaster in the Making

World Medical & Health Policy, 2011
AbstractAnti‐microbial drug resistance (AMR or AMDR) is a complex multi‐dimensional and systemic failure in health education, social behavior, health care legislation and/or policies and practices. AMDR is a life threatening infection extending beyond national boundaries.
Arnauld Nicogossian   +3 more
openaire   +2 more sources

Construction of Canthaxanthin-Producing Yeast by Combining Spatiotemporal Regulation and Pleiotropic Drug Resistance Engineering.

ACS Synthetic Biology, 2021
The ketocarotenoid canthaxanthin has important applications in the feed industry. Its biosynthesis using microbial cell factories is an attractive alternative to the current chemical synthesis route.
Mingkai Chen   +3 more
semanticscholar   +1 more source

Microbial Drug Resistance

1955
Publisher Summary It is unfeasible and unnecessary to coerce the complex biological events contributing to the origin of resistance into a single theory. Experimental evidence suggests that a few models define most examples of resistance development, particularly if the models are so combined as to provide either genotypic or phenotypic alterations ...
V, BRYSON, W, SZYBALSKI
openaire   +2 more sources

Microbial and viral drug resistance mechanisms

Trends in Microbiology, 2002
Microorganisms and viruses have developed numerous resistance mechanisms that enable them to evade the effect of antimicrobials and antivirals. As a result, many have become resistant to almost every available means of treatment. This problem, although not new, is becoming increasingly acute and it is now clear that a fundamental understanding of the ...
Kenneth S, McKeegan   +2 more
openaire   +2 more sources

Biocides, drug resistance and microbial evolution

Current Opinion in Microbiology, 2001
Antimicrobial biocides are widely used in critical human health situations in which rigorous infection control is needed. Increasingly, biocidal agents are being marketed for home use, although there is little evidence that they significantly improve home hygiene. Biocide resistance mechanisms share many themes with antibiotic resistance mechanisms.
D G, White, P F, McDermott
openaire   +2 more sources

Microbial resistance to drug therapy: A review

American Journal of Infection Control, 1997
Microbial resistance to the antimicrobials in standard use is becoming more prevalent. A historical perspective frames further discussion. Bacterial resistance is most common, but resistance has been identified in fungi, viruses, and parasites. Resistance is a complex phenomenon that involves the microorganism, the environment, and the patient ...
F L, Cohen, D, Tartasky
openaire   +2 more sources

Analysis of the Drug Resistance of Carbapenem-Resistant Klebsiella pneumoniae in the China Antimicrobial Resistance Surveillance Trial Program, 2007–2018

Microbial Drug Resistance, 2020
Objective: To analyze the drug resistance data of carbapenem-resistant Klebsiella pneumoniae (CRKP) collected in 19 tertiary hospitals in the China Antimicrobial Resistance Surveillance Trial Program from 2007 to 2018.
Lei Gao, Y. Lv, Yun Li
semanticscholar   +1 more source

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