Results 51 to 60 of about 4,184,296 (300)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Value-addition of water hyacinth and para grass through pyrolysis and hydrothermal liquefaction

Carbon Resources Conversion, 2019
Hydrothermal liquefaction (HTL) and pyrolysis (Py) of Loktak lake biomass mixture of water hyacinth (WH) and para grass (PG) were carried out at 260–300 °C and 300–500 °C to compare the products yield and chemical characteristics of the products. In case
Dinabandhu Sahoo, Ayushi Awasthi, Vaibhav Dhyani, Bijoy Biswas, Jitendra Kumar, Yenumala Sudhakara Reddy, V.P. Adarsh, Anoop Puthiyamadam, Kiran Kumar Mallapureddy, Rajeev K. Sukumaran, Sabeela Beevi Ummalyma, Thallada Bhaskar   +11 more
doaj   +1 more source

Impact of intercropping on the coupling between soil microbial community structure, activity, and nutrient-use efficiencies [PDF]

PeerJ, 2019
Sugarcane-soybean intercropping has been widely used to control disease and improve nutrition in the field. However, the response of the soil microbial community diversity and structure to intercropping is not well understood.
Tengxiang Lian, Yinghui Mu, Jian Jin, Qibin Ma, Yanbo Cheng, Zhandong Cai, Hai Nian   +6 more
doaj   +2 more sources

Impact of inoculum type on the microbial community and power performance of urine-fed microbial fuel cells [PDF]

, 2020
Bacteria are the driving force of the microbial fuel cell (MFC) technology, which benefits from their natural ability to degrade organic matter and generate electricity. The development of an efficient anodic biofilm has a significant impact on the power
Salar-Garcia, Maria Jose, Kurt, Halil, Halil Kurt, Kartik Chandran, Obata, Oluwatosin, Maria Jose Salar-Garcia, Chandran, Kartik, Ieropoulos, Ioannis A., Oluwatosin Obata, John Greenman, Ioannis A. Ieropoulos, Greenman, John   +11 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Leveraging artificial intelligence for efficient microbial production

Bioresource Technology
Microbial production is a sustainable and economical approach to producing value-added compounds by functional enzyme application, precise metabolism regulation, effective strain development, and optimal bioprocess control. However, practical microbial production faces multiple problems.
Xinyu Gong, Jianli Zhang, Qi Gan, Wei Ruan, Tianming Liu, Yajun Yan   +5 more
openaire   +2 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Effect of feeding Yucca schidigera extract and a live yeast on the rumen microbiome and performance of dairy cows fed a diet excess in rumen degradable nitrogen

Animal, 2023
Nitrogen (N) loss from livestock agriculture via ammonia and nitrous oxide can reduce feed efficiency, production and negatively affect the environment. One option to reduce N loss is to add dietary supplements such as Yucca schidigera extract which has ...
C.A. Johnson, T.J. Snelling, J.A. Huntington, J. Taylor-Pickard, H.E. Warren, L.A. Sinclair   +5 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source