Results 101 to 110 of about 44,781 (234)

Limosilactobacillus reuteri enhances ovarian function and female fertility

iMeta, EarlyView.
Limosilactobacillus reuteri Y15 (LRY15)‐derived polyunsaturated fatty acids (PUFAs) restore follicular cell‐cell junctions and fertility. LRY15, isolated from the intestine of alginate oligosaccharides (AOS)‐dosed mice, improves ovarian function and fertility in cisplatin‐induced subfertile mice.
Yongsheng Hao, Yukang Li, Shen Li, Juanli Huo, Ninghang You, Lei Li, Yue Jiang, Weidong Zhang, Huakai Wei, Qingyuan Sun, Yunwei Pang, Xunsi Qin, Tao Tu, Huoqing Huang, Jian Tian, Pengfei Zhang, Yaru Wang, Xinxin Xu, Bin Yao, Wei Shen, Xing Qin, Huiying Luo, Yong Zhao   +22 more
wiley   +1 more source

Diversity of Microbial Eukaryotes Along the West Antarctic Peninsula in Austral Spring. [PDF]

Front Microbiol, 2022
Grattepanche JD, Jeffrey WH, Gast RJ, Sanders RW.   +3 more
europepmc   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

Seagrass Colonization Alters Diversity, Abundance, Taxonomic, and Functional Community Structure of Benthic Microbial Eukaryotes. [PDF]

Front Microbiol, 2022
Pan Y, Li G, Su L, Zheng P, Wang Y, Shen Z, Chen Z, Han Q, Gong J.   +8 more
europepmc   +1 more source

Macrophage extracellular vesicles deliver Mef2d proteins to aggravate Bacteroides fragilis pathogenicity in type 2 diabetes arterial calcification

Interdisciplinary Medicine, EarlyView.
Bacteroides fragilis is associated with type 2 diabetes (T2D) arterial calcification and can be activated by macrophage‐derived extracellular vesicles (EVs). BF takes up EVs via receptor‐mediated endocytosis, and activation is induced by EV‐derived Mef2d, thereby inhibiting ArsR family transcriptional regulator transcription.
Cong Chen, Rong He, Jirong Luo, Zhengfeng Liang, Qunwen Pan, Shuangquan Liu, Jingsong Cao   +6 more
wiley   +1 more source

DAPI staining and DNA content estimation of nuclei in uncultivable microbial eukaryotes (Arcellinida and Ciliates). [PDF]

Eur J Protistol, 2021
Munyenyembe K, Timmons C, Weiner AKM, Katz LA, Yan Y.   +4 more
europepmc   +1 more source

Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance

Interdisciplinary Medicine, EarlyView.
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang, Tong Jiang, Yaling Lin, Wei Zhang, Hongjie Fan, Minjie Yang, Bingzhe Li, Yaozu Liu, Changyu Li, Xuran Jin, Wen Zhang, Zhiping Yan, Qianqian Zhao, Xuefeng Kan, Xudong Qu   +14 more
wiley   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Protocol for single-cell isolation and genome amplification of environmental microbial eukaryotes for genomic analysis. [PDF]

STAR Protoc, 2022
Ciobanu D, Chan S, Ahrendt S, Quandt CA, Benny GL, Smith ME, James TY, Cheng JF.   +7 more
europepmc   +1 more source