Results 141 to 150 of about 720,693 (225)

Importance of eukaryotes in shaping microbial benthic communities in Charente-maritime marshes, France

open access: yes
International audienceMarshes are wetlands known for providing major ecosystem services in terms of water quality and human activities. These ecosystem services are mainly provided by marshes' benthic community, composed of prokaryotes (bacteria and ...
Bouchard, Andréa   +5 more
core   +1 more source

Structural and mutational analysis of Methanosarcina mazei prenylated FMN synthase reveals the basis of its unique prenyl donor substrate specificity

open access: yesThe FEBS Journal, EarlyView.
Some prenylated flavin mononucleotide (prFMN) synthases exceptionally prefer dimethylallyl phosphate (DMAP) over dimethylallyl diphosphate (DMAPP), which is a common prenyl donor substrate for many prenyltransferases. Structural and mutagenic analyses of Methanosarcina mazei prFMN synthase, which prefers DMAP but can also accept DMAPP, elucidated its ...
Sou Fukuhara   +5 more
wiley   +1 more source

Breaking the Boring Billion

open access: yesGeophysical Monograph Series, Page 487-501., 2021

Exploring the links between Large Igneous Provinces and dramatic environmental impact

An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Charles W. Diamond   +3 more
wiley  

+1 more source

Insights into tandem dioxygenases—copper radical oxidases in fungal Phytopathogens of the Colletotrichum acutatum species complex

open access: yesThe FEBS Journal, EarlyView.
In Colletotrichum acutatum species complex, conserved ring‐cleavage dioxygenases located adjacent to AA5_2 enzymes were investigated as potential redox partners. Biochemical analyses identified the dioxygenases as intradiol‐cleaving enzymes preferentially oxidizing methyl‐substituted catechols, while AA5_2 enzymes displayed weak alcohol oxidase ...
Radka Končitíková   +7 more
wiley   +1 more source

Selective autophagy pathways in ageing and neurodegeneration: Emerging roles for mitophagy and nucleophagy

open access: yesThe FEBS Journal, EarlyView.
As we age, cells gradually accumulate damage, which can contribute to disease and neurodegeneration. This review explores how two cellular recycling processes, mitophagy and nucleophagy, remove damaged mitochondria and nuclear material, respectively, to maintain cell health and long‐term neuronal homeostasis.
Maria Markaki, Nektarios Tavernarakis
wiley   +1 more source

Breaking the ice: multiple origins of ice‐binding/antifreeze proteins

open access: yesThe FEBS Journal, EarlyView.
Ice‐binding proteins (IBPs) evolved independently in many organisms during Cenozoic cooling and glaciation. In flounders, α‐helical IBPs evolved from an antiviral protein, while similar IBPs arose independently from different progenitors in three other fish lineages.
Laurie A. Graham, Peter L. Davies
wiley   +1 more source

Lignan‐rich Norway spruce (Picea abies) resin extract exhibits anti‐inflammatory, skin‐regenerative and anti‐acne effects: In vitro, in silico, biocompatibility and exploratory clinical findings

open access: yesInternational Journal of Cosmetic Science, EarlyView.
GA text A 30% Picea abies resin extract cream combined antimicrobial, anti‐inflammatory and early pro‐repair activities relevant to acne‐prone skin. The formulation showed strong activity against Cutibacterium acnes, reduced inflammatory cytokines and demonstrated promising tolerability and efficacy in an exploratory in‐use study. Abstract Objective To
Simone Parrotta   +4 more
wiley   +1 more source

Multi‐omics analyses reveal host–microbe interactions in atopic dermatitis and psoriasis

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Atopic dermatitis (AD) and psoriasis (PSO) are chronic inflammatory skin diseases with complex host–microbe interactions. This study analysed skin samples from patients and healthy individuals using integrated microbial and transcriptomic profiling. Both diseases showed disrupted fungal–bacterial interactions and alterations in host immune responses ...
Ying Yang   +8 more
wiley   +1 more source

Engineered Yarrowia lipolytica inducing gene silencing confers control ability against gray mold in plants

open access: yesJournal of Integrative Plant Biology, EarlyView.
Engineered the plant‐colonizing yeast Yarrowia lipolytica to produce and deliver double‐stranded RNAs targeting key genes of the gray mold fungus Botrytis cinerea produced a ‘living factory’ that continuously synthesizes and releases gene‐silencing molecules on plant surfaces, effectively suppressing the pathogen.
Mengjie Liu   +5 more
wiley   +1 more source

Bridging the gap between genomic, phenotypic, and modeling data in picophytoplankton–virus interactions

open access: yesJournal of Phycology, EarlyView.
Abstract We present a comprehensive synthesis of recent developments in methodological approaches to combine experimental and genomic studies of picophytoplankton–virus interactions. This synthesis will not only enhance our understanding of these relationships but also stimulate new hypotheses for the interpretation of metagenomic data and enrich ...
Luisa Listmann   +11 more
wiley   +1 more source

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