Results 201 to 210 of about 91,684 (289)
European Journal of Haematology, EarlyView.ABSTRACT The interplay between the commensal microbiota and the mammalian immune system may influence the outcomes of T cell‐driven cancer immunotherapies. However, clinical studies supporting microbiota‐based interventions in chimeric antigen receptor T‐cell (CAR‐T) therapy remain scarce.
Rafael Hernani +22 more
wiley +1 more source
Combining morphology, behaviour and genomics to understand the evolution and ecology of microbial eukaryotes. [PDF]
Philos Trans R Soc Lond B Biol Sci, 2019 Keeling PJ.
europepmc +1 more source
Diversity of bacterial endosymbionts in siphonous and siphonocladalean green algae [PDF]
, 2009 De Clerck, Olivier +3 more
core
The FEBS Journal, EarlyView.Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner +13 more
wiley +1 more source
Pangloss: A Tool for Pan-Genome Analysis of Microbial Eukaryotes. [PDF]
Genes (Basel), 2019 McCarthy CGP, Fitzpatrick DA.
europepmc +1 more source
Cas9 beyond CRISPR – SUMOylation, effector‐like potential and pathogenic adaptation
The FEBS Journal, EarlyView.This Viewpoint explores the possibility that Cas9, beyond its canonical role in CRISPR immunity, may act as a host‐modulating effector during infection by Cas9‐encoding bacteria. Such a nucleomodulin‐like function could be influenced by eukaryotic post‐translational modifications, particularly SUMOylation, with potential implications for host–pathogen ...
Umut Sahin
wiley +1 more source
The structural, functional, and therapeutic potential of metacaspases in fungi and protozoa
The FEBS Journal, EarlyView.Metacaspases are Ca2+‐dependent cysteine proteases whose structural characteristics, particularly calcium binding and autocatalytic processing, govern their activation and biological functions. These enzymes differ among microorganisms and regulate their cell cycles, making them excellent targets for drug development.
Ane C. M. Duarte +9 more
wiley +1 more source
Microbial eukaryotes in the suboxic chemosynthetic ecosystem of Movile Cave, Romania. [PDF]
Environ Microbiol Rep, 2019 Reboul G +4 more
europepmc +1 more source
Bacterial Extracellular Vesicles in the Pathogenesis and Treatment of Liver Diseases
Journal of Gastroenterology and Hepatology, EarlyView.Liver diseases are a major global health challenge, with current treatments inadequate. This review highlights the role of bacterial extracellular vesicles in liver inflammation, fibrosis, and metabolism. We also explore these from commensals and probiotics, their protective effects, and discuss research challenges and future therapeutic potential ...
Yakun Li +3 more
wiley +1 more source
Using single-cell transcriptomics to understand functional states and interactions in microbial eukaryotes. [PDF]
Philos Trans R Soc Lond B Biol Sci, 2019 Ku C, Sebé-Pedrós A.
europepmc +1 more source