Results 71 to 80 of about 91,684 (289)

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Microbial Eukaryotes in Natural and Artificial Salt Marsh Pools

Coasts
Microscopic eukaryotes are important components of coastal wetland ecosystems. The goal of this study was to investigate the diversity of microeukaryotes in the tidal pools of a New Jersey salt marsh and to compare the assemblages of natural and ...
Marina Potapova, Daiana Markarian, Abigail King, Laura Aycock   +3 more
doaj   +1 more source

Prevalence of partnerships between bacteria and ciliates in oxygen-depleted marine water columns

Frontiers in Microbiology, 2012
Symbioses between Bacteria, Archaea, and Eukarya in deep-sea marine environments represent a means for eukaryotes to exploit otherwise inhospitable habitats.
William D Orsi, Sophie eCharvet, Peter eVdacny, Joan M Bernhard, Virginia P Edgcomb   +4 more
doaj   +1 more source

Chemical markers for rumen methanogens and methanogenesis [PDF]

, 2013
Peer reviewedPublisher ...
Bessa, Bhagwat, Brulc, C.A. McCartney, Casto Montoya, Chen, Chilliard, Dehareng, Dehority, Dewhurst, Dewhurst, Diedrich, Dijkstra, Ding, Fievez, Firkins, Frey, Fritze, Gill, Gill, Gu, Guo, Hegarty, Hildenbrand, Hook, Hopmans, Huguet, I.D. Bull, Janssen, Jenkins, Kim, Koga, Koga, Lee, Leng, Liu, Mao, Mathai, McCartney, McGeough, Mohammed, Morgavi, Mosoni, Odongo, Pancost, Pei, Pinares-Patiño, Polidori, R.J. Dewhurst, Schouten, Schouten, Sharp, Shimada, Shin, Shingfield, Stouthamer, Thauer, Tymensen, Valentine, Vlaeminck, Vlaeminck, Weijers, Zhou, Zhou   +63 more
core   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

Dataset complexity impacts both MOTU delimitation and biodiversity estimates in eukaryotic 18S rRNA metabarcoding studies

Environmental DNA, 2022
How does the evolution of bioinformatics tools impact the biological interpretation of high‐throughput sequencing datasets? For eukaryotic metabarcoding studies, in particular, researchers often rely on tools originally developed for the analysis of 16S ...
Alejandro De Santiago, Tiago José Pereira, Sarah L. Mincks, Holly M. Bik   +3 more
doaj   +1 more source

Ciliary contact interactions dominate surface scattering of swimming eukaryotes

, 2012
Interactions between swimming cells and surfaces are essential to many microbiological processes, from bacterial biofilm formation to human fertilization.
Dunkel, Jörn, Goldstein, Raymond E., Kantsler, Vasily, Polin, Marco   +3 more
core   +1 more source

Pole-to-Pole Connections : Similarities between Arctic and Antarctic Microbiomes and Their Vulnerability to Environmental Change [PDF]

, 2017
Acknowledgments JK acknowledges the Carl Zeiss foundation for PhD funding, the Marie-Curie COFUND-BEIPD PostDoc fellowship for PostDoc funding, FNRS travel funding and the logistical and financial support by UNIS.
Bahram, Mohammad, Bork, Peer, Camacho, Antonio, Convey, Peter, Dietrich, Daniel R., Hildebrand, Falk, Jungblut, Anne D., Kleinteich, Julia, Küpper, Frithjof C., Pearce, David A., Quesada, Antonio, Vincent, Warwick F., Voigt, Anita Y., Wood, Susanna A., Zarfl, Christiane   +14 more
core   +4 more sources

Unveiling new microbial eukaryotes in the surface ocean

Current Opinion in Microbiology, 2008
A decade after molecular techniques were used to discover novel bacteria and archaea in the oceans, the same approach has revealed a wealth of new marine eukaryotic microbes. The approach has been particularly successful with the smallest eukaryotes, where morphological and culture approaches frequently fail. Analysis of samples from the surface ocean,
Massana, Ramon, Pedrós-Alió, Carlos
openaire   +3 more sources

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source