Results 221 to 230 of about 876,917 (302)

Model‐Driven Monitoring and Parameter‐Based Development of an Escherichia coli Fed‐Batch Process for Production of a Fab Antibody Fragment Across Scales

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Maintaining consistent cellular physiology during bioprocess scale‐up or scale‐down is key to developing robust processes. However, the reliability of scale‐down bioreactor systems remains debated. Although the calibration of physiological parameters in mechanistic models across scales has been proposed as a scale‐down strategy, few studies ...
Fabian Schröder‐Kleeberg   +8 more
wiley   +1 more source

Automated Data‐Efficient Symbolic Regression for Interpretable Bioprocess Model Development

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Bioprocessing is central to the sustainable manufacture of pharmaceuticals, food products, and renewable chemicals. Consequently, developing high‐fidelity kinetic models to facilitate accurate process prediction, optimisation, and scale‐up is a top research priority.
Luca Riezzo   +3 more
wiley   +1 more source

Effects of microbial fermentation on the anti-inflammatory activity of Chinese yam polysaccharides. [PDF]

open access: yesFront Nutr
Yang J   +11 more
europepmc   +1 more source

Combinatorial Metabolic Engineering of Alkane Biosynthesis in the Osmotolerant Yeast Debaryomyces hansenii CBS 767

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Debaryomyces hansenii is a yeast with diverse potential applications like producing oleochemicals from biomass. Yet, combinatorial metabolic engineering in D. hansenii is limited because, like many nonconventional organisms, key genomic data and genetic elements are missing. Here, we report phenotypic characterization, genomic integration loci,
Zekun Li   +3 more
wiley   +1 more source

Comparison of Anti-Renal Fibrosis Activity of <i>Eucommiae cortex</i> Extract and Its Microbial Fermentation Products. [PDF]

open access: yesPharmaceuticals (Basel)
He Z   +9 more
europepmc   +1 more source

Reducing Cooling Costs for Sustainable Food Biomanufacturing With Thermotolerant Cupriavidus necator H16 Mutant

open access: yesBiotechnology and Bioengineering, EarlyView.
With a thermotolerant C. necator mutant the SCP production costs can be decreased by $0.98/kg. ABSTRACT Autotrophic CO2 conversion to Single Cell Protein (SCP) using H2 and O2 is gaining commercial traction for food and feed production. Cupriavidus necator H16 is a key chassis organism for this “knallgas” fermentation, but industrial operation is ...
Lars Puiman   +2 more
wiley   +1 more source

Functional Diversity and Oleaginous Potential of Fungal Strains From Hawaiian Soil Ecosystems

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Fungi represent an important but underexplored resource for microbial lipid production, including nutritionally valuable polyunsaturated fatty acids. Hawaiian soils, shaped by volcanic parent materials and strong environmental gradients, provide a unique setting for discovering functionally diverse fungal strains with distinct metabolic traits.
Yu Wang   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy