Results 61 to 70 of about 1,109,995 (249)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Nutrient-Limited Operational Strategies for the Microbial Production of Biochemicals

open access: yes, 2022
Limiting an essential nutrient has a profound impact on microbial growth. The notion of growth under limited conditions was first described using simple Monod kinetics proposed in the 1940s.
Rajpurohit, Hemshikha   +3 more
core   +1 more source

BMT305 – Microbial Physiology (Fisiologi Mikrob) [PDF]

open access: yes
Second Semester Examination 2023/2024 Academic Session July/August 2024 BMT305 – Microbial Physiology (Fisiologi Mikrob) Duration : 2 hours (Masa : 2 ...
PPSKJ, Pusat Pengajian Sains Kajihayat
core   +1 more source

Urease promotes pH homeostasis and growth of Staphylococcus aureus in skin-like conditions

open access: yesJournal of Bacteriology
Staphylococcus aureus is a Gram-positive opportunistic pathogen and a leading cause of skin and soft tissue infections (SSTIs). S. aureus colonizes approximately 20–30% of the population and transiently colonizes the skin.
Flavia G. Costa, Alexander R. Horswill
doaj   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Physiology

open access: yes, 1983
v.1165 hal.; 27 ...
Physiology
core  

Strain Improvement and Microbial Biosynthesis

open access: yes
Recent industrial biotechnology developments have revealed the enormous potential of microbial fermentation as an alternative to the chemical syntheses of many valuable compounds [...
Penka Petrova, Kaloyan Petrov
core   +1 more source

Saccharomyces cerevisiae Culture’s Dose–Response Effects on Ruminal Nutrient Digestibility and Microbial Community: An In Vitro Study

open access: yes, 2023
Supplementation with saccharomyces cerevisiae culture products (SCs) has shown effectiveness in alleviating or improving the health and productivity of ruminants at a high risk of digestive and metabolic problems as a consequence of their physiological ...
Yanfang Liu   +7 more
core   +1 more source

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