Results 101 to 110 of about 308,196 (199)

Gut Microbiota Colonization in Early Life Influences Susceptibility to Adulthood Hepatic Lipid Accumulation in High‐Fat‐Diet‐Fed Mice

open access: yesAdvanced Science, EarlyView.
This study indicates that perinatal antibiotic exposure elevates susceptibility to high‐fat‐diet‐induced hepatic lipid accumulation via disrupting early‐life gut microbiota colonization. The decreased Lactobacillus colonization inhibits primary‐to‐secondary bile acid conversion, lowering secondary bile acids, enhancing adulthood intestinal lipid ...
Yan‐Yan Zhu   +11 more
wiley   +1 more source

Soil biodiversity: functions, threats and tools for policy makers [PDF]

open access: yes, 2010
Human societies rely on the vast diversity of benefits provided by nature, such as food, fibres, construction materials, clean water, clean air and climate regulation.
Benito, Patricia   +8 more
core   +2 more sources

The Type III Secretion System (T3SS) of Escherichia Coli Promotes Atherosclerosis in Type 2 Diabetes Mellitus

open access: yesAdvanced Science, EarlyView.
Large‐scale studies indicate a strong relationship between the gut microbiome, type 2 diabetes mellitus (T2DM), and atherosclerotic cardiovascular disease (ASCVD). Here, a higher abundance of the type III secretion system (T3SS) virulence factors of Enterobacteriaceae/Escherichia‐Shigella in patients with T2DM‐related‐ASCVD, which correlates with their
Yao‐Yuan Zhang   +15 more
wiley   +1 more source

Ratiometric control for differentiation of cell populations endowed with synthetic toggle switches

open access: yes, 2019
We consider the problem of regulating by means of external control inputs the ratio of two cell populations. Specifically, we assume that these two cellular populations are composed of cells belonging to the same strain which embeds some bistable memory ...
di Bernardo, Mario   +2 more
core   +1 more source

4D Biofabrication of Magnetically Augmented Callus Assembloid Implants Enables Rapid Endochondral Ossification via Activation of Mechanosensitive Pathways

open access: yesAdvanced Science, EarlyView.
Magnetically augmented biohybrid cartilaginous microtissues enable remote microtissue motion control and assembly as well as targeted differentiation. This study demonstrates accelerated endochondral ossification under magnetic stimulation, highlighting cartilaginous assembloid constructs’ ability to retain long‐term magnetic properties.
Konstantinos Ioannidis   +13 more
wiley   +1 more source

Dimethyl Itaconate Alleviates Escherichia coli‐Induced Endometritis Through the Guanosine‐CXCL14 Axis via Increasing the Abundance of norank_f_Muribaculaceae

open access: yesAdvanced Science, EarlyView.
The research findings indicate that dimethyl itaconate (DI) alleviates Escherichia coli (E. coli) induced endometritis by modulating the gut microbiota and enriching the abundance of norank_f_Muribaculaceae, thereby increasing the production of guanosine.
Yuhang He   +6 more
wiley   +1 more source

Soil biota in grassland, its ecosystem services and the impact of management [PDF]

open access: yes, 2007
In the search for sustainable grassland systems, self-regulating processes in the soil become increasingly important. Soil biota play an important role in these processes and in the provision of various ecosystem services. For grassland systems important
Murray, P.J.   +2 more
core  

Nanoneedle‐Based Electroporation for Efficient Manufacturing of Human Primary Chimeric Antigen Receptor Regulatory T‐Cells

open access: yesAdvanced Science, EarlyView.
Low reproducibility and inefficient gene transfer hamper clinical manufacturing of chimeric antigen receptor regulatory T cells (CAR Tregs). Nanoneedle mediated electroporation generates primary human CAR Tregs under good manufacturing practice conditions with superior efficiency compared to viral transduction.
Ningjia Sun   +12 more
wiley   +1 more source

Efficient imaging and computer vision detection of two cell shapes in young cotton fibers

open access: yesApplications in Plant Sciences, Volume 10, Issue 6, November-December 2022., 2022
Abstract Premise The shape of young cotton (Gossypium) fibers varies within and between commercial cotton species, as revealed by previous detailed analyses of one cultivar of G. hirsutum and one of G. barbadense. Both narrow and wide fibers exist in G. hirsutum cv.
Benjamin P. Graham   +5 more
wiley   +1 more source

Parallel changes in gut microbiome composition and function in parallel local adaptation and speciation [PDF]

open access: yes, 2019
The processes of local adaptation and ecological speciation are often strongly shaped by biotic interactions such as competition and predation. One of the strongest lines of evidence that biotic interactions drive evolution comes from repeated divergence
Rennison, Diana   +2 more
core  

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