Results 131 to 140 of about 308,196 (199)

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

open access: yesAggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai   +6 more
wiley   +1 more source

Phototherapy via Modulation of β‐Amyloid in Combating Alzheimer's Disease

open access: yesAggregate, EarlyView.
This review introduces the light‐regulated Aβ aggregation, highlighting four applications: photodynamic therapy (PDT), photothermal therapy (PTT), photopharmacology, and photobiomodulation (PBM) systems. It also summarizes the current issues and proposes the prospects of photo‐induced modulation of Aβ aggregation and clearance as a therapeutic strategy
Yunhua Zhang   +4 more
wiley   +1 more source

An argument for using anaerobes as microbial cell factories to advance synthetic biology and biomanufacturing

open access: yesAIChE Journal, EarlyView.
Abstract Anaerobes thrive in the absence of oxygen and are an untapped reservoir of biotechnological potential. Therefore, bioprospecting efforts focused on anaerobic microbial diversity could rapidly uncover new enzymes, pathways, and chassis organisms to drive biotechnology innovation.
Thomas S. Lankiewicz   +3 more
wiley   +1 more source

Investigating Social Immunity in Swarming Locusts via a Triple Animal–Robot–Pathogen Hybrid Interaction

open access: yesAdvanced Intelligent Systems, EarlyView.
This study explores social immunity in gregarious locusts using a groundbreaking animal–robot–pathogen interaction model. By comparing locust responses to biomimetic agents mimicking healthy and infected individuals, significant behavioral changes are revealed.
Donato Romano, Cesare Stefanini
wiley   +1 more source

Multi‐Module Micro/Nanorobots for Biomedical and Environmental Remediation Applications

open access: yesAdvanced Intelligent Systems, EarlyView.
Multi‐module microrobots (MNRs) have overcome the limitations of single‐module systems by integrating components such as propeller, actuator, manipulator, and imaging modalities. They show promise in biomedical applications, such as targeted drug delivery and tissue repair, as well as in environmental remediation, including pollutant removal.
Bairong Zhu   +4 more
wiley   +1 more source

Soil biome variation of Lupinus nipomensis in wet‐cool vs. dry‐warm microhabitats and greenhouse

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise Environmental DNA (eDNA) can be used to determine the composition of the soil biome community, revealing beneficial and antagonistic microbes and invertebrates associated with plants. eDNA analyses can complement traditional soil community studies, offering more comprehensive information for conservation practitioners. Studies are also
Peter T. Nguyen   +5 more
wiley   +1 more source

Current updates of CRISPR/Cas9‐mediated genome editing and targeting within tumor cells: an innovative strategy of cancer management

open access: yesCancer Communications, Volume 42, Issue 12, Page 1257-1287, December 2022., 2022
Abstract Clustered regularly interspaced short palindromic repeats‐associated protein (CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust, accurate, efficient and programmable method for genome targeting and editing. This innovative and revolutionary technique can play a significant role in animal modeling, in vivo genome
Khaled S. Allemailem   +6 more
wiley   +1 more source

A Sequential Release Micro‐nano System for Colitis Therapy via Gut Microbiota and Immune Regulation

open access: yesAngewandte Chemie, EarlyView.
The micro‐nano system achieves the sequential release of drugs in response to gut microbiota and reactive oxygen species (ROS). Inulin prebiotics restore gut microbiota balance. Selenium compounds scavenge ROS and promote macrophage polarization, while 3‐oxolithocholic acid suppresses TH17‐cell differentiation. As a multifactorial therapeutic approach,
Dongdong Zhu   +9 more
wiley   +2 more sources

Gut Microbiome Pilot Study of Patients With CHARGE Syndrome and Sibling Controls

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Difficulties with feeding and digestion are common in individuals with CHARGE syndrome. Animal models with CHD7 gene variants demonstrate abnormal gut innovation and dysmotility. Our pilot study evaluated whether individuals with CHARGE syndrome have differences in their gut microbiome compared to unaffected siblings.
Emily R. Chedrawe   +5 more
wiley   +1 more source

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