Results 141 to 150 of about 535,232 (307)

A dual light-controlled co-culture system enables the regulation of population composition

Synthetic and Systems Biotechnology
With the development of metabolic engineering, increasing requirements for efficient microbial biosynthesis call for establishment of multi-strain co-culture system.
Wei Jiang, Yijian Guo, Xuanshuo Liang, Ying Zhang, Jianning Kang, Zhengxin Jin, Bin Ning   +6 more
doaj   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Ecology and Evolutionary Biology as Frameworks to Study Wine Fermentations

Microbial Biotechnology
Winemaking has leveraged microbiology to enhance wine quality, typically by engineering and inoculating individual yeast strains with desirable traits. However, yeast strains do not grow alone during wine fermentation, rather they are embedded in diverse
Ignacio Belda, Belen Benitez‐Dominguez, Sergio Izquierdo‐Gea, Jean C. C. Vila, Javier Ruiz   +4 more
doaj   +1 more source

A Microfluidic Multiplex Sorter for Strain Development

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
A new multiplex method for high‐throughput screening of yeast strains based on glucoamylase production is presented. Droplets containing single mutant yeast cells are incubated for enzyme production. A sorting platform divides mutants by their high‐ and mid‐activity levels.
Chiara Leal‐Alves, Sebastien Dumont, Zhiyang Deng, Sarah Alkhaldi, Ziuwin Leung, Michelle Oeser, Steve C. C. Shih   +6 more
wiley   +1 more source

A synthetic microbial consortium protects against obesity by regulating vitamin B6 metabolism

Gut Microbes
Constructing synthetic microbial consortia is a challenging task but holds enormous potential for various applications. Our previous droplet-based microfluidic approach allowed for the isolation of bacteria that could utilize metabolites from an ...
Xiuzhao Chen, Mengxue Gao, Lina Wang, Guifen Qiang, Yili Wu, He Huang, Guangbo Kang   +6 more
doaj   +1 more source

Different evolutionary paths to complexity for small and large populations of digital organisms

, 2016
A major aim of evolutionary biology is to explain the respective roles of adaptive versus non-adaptive changes in the evolution of complexity. While selection is certainly responsible for the spread and maintenance of complex phenotypes, this does not ...
Adami, Christoph, LaBar, Thomas
core   +4 more sources

Quantitative Assessment of Gut and Vascular Barriers in TTOP, a Cartridge‐Based Bicompartmental Culture Platform

Advanced Materials Technologies, EarlyView.
The modular, versatile, and standardized cartridge‐based culture module allows to replicate gut and vascular barriers. Its conventional handling requirements facilitate adoption by non‐technical users, while the design allows safe manipulation and retrieval of samples for permeability assays and endpoint analysis.
Lorenzo Pietro Coppadoro, Maria Lombardi, Sabrina Nicolò, Alessandra Maria Anna Rando, Gianfranco Beniamino Fiore, Chiara Foglieni, Monica Soncini   +6 more
wiley   +1 more source

Smart Sampling Capsule for Capture and Detection of Enteric Pathogens in the Small Intestine

Advanced Materials Technologies, EarlyView.
An ingestible smart sampling capsule for capturing asymptomatic enteric pathogens at their primary sites of interaction within the small intestine. This capability enables non‐invasive detection of early pathogen colonization within the gut environment prior to fecal shedding, providing a robust approach for pathogen surveillance and microbiome studies.
Akshay Krishnakumar, Devendra Sarnaik, Nicholas L. F. Gallina, Robyn R. McCain, Christa Crain, Arun K. Bhunia, Rahim Rahimi   +6 more
wiley   +1 more source

Population Dynamics of Escherichia coli Growing under Chemically Defined Media

Scientific Data
Bacterial population dynamics are essential for understanding microbial survival strategies and optimizing cell culture systems. However, the variation in these dynamics across different environmental conditions remains largely unexplored.
Honoka Aida, Bei-Wen Ying
doaj   +1 more source

Multitasking Smart Intestinal Capsule Robot: A Cutting‐Edge Platform for Sampling, Diagnosis, and Therapy

Advanced Robotics Research, EarlyView.
Gut microbiota and biomarkers are linked to diseases like neurological disorders and metabolic syndromes. Ingestible capsule robots enable minimally invasive gut health assessment. This article proposes a promising direction for the advancement of capsule robots, integrating in situ sampling, real‐time diagnostics, and personalized therapy.
Xizong Chen, Libing Huang, Lei Ren, Miao Wang   +3 more
wiley   +1 more source