Results 141 to 150 of about 369,608 (276)
Editorial: Evolution of Animal Microbial Communities in Response to Environmental Stress
Frontiers in Microbiology, 2022 Teresa Nogueira +4 more
doaj +1 more source
Advanced Science, EarlyView.Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian +26 more
wiley +1 more source
Advanced Science, EarlyView.BLP‐trained macrophages show augmented resistance to infection, but their mechanisms remain unclear. scRNA‐seq identified 13 BMDM subsets, with two novel anti‐inflammatory/antibacterial subpopulations (C5/C7) emerging post‐BLP training. BLP training activates NRF2, attenuates oxidative stress/ferroptosis, and boosts glycolysis/OXPHOS. Adoptive transfer
Yantong Wan +13 more
wiley +1 more source
Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism
Advanced Science, EarlyView.Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang +4 more
wiley +1 more source
MICROBIAL ECOLOGY OF SOILS FROM WILKES LAND, ANTARCTICA : I. THE BACTERIAL POPULATION AND ITS ACTIVITY IN RELATION TO DISSOLVED ORGANIC MATTER (Eleventh Symposium on Polar Biology)During a comprehensive research program carried out on soils from the Antarctic Continent (Casey Station, Wilkes Land) emphasis was laid on the bacterial population, its state of activity and corresponding relationships to particulate and dissolved organic nutrients. The bacterial population is characterized by epifluorescence microscopy with regard to
openaire
Advanced Science, EarlyView.Circardian rhythm disorder (CRD) causes abnormal expression of intestinal Period 2 (Per2) gene, which compromising intestinal barrier integrity and altering the gut microenvironment. Microbiota dysbiosis and aberrant metabolites production drive central inflammation, impair neurogenesis, and promote functional deficits, ultimately facilitating the ...
Huiliang Zhang +16 more
wiley +1 more source
Advanced Science, EarlyView.Here, our novel model that integrates metabolism with motility dynamics reveals that microalgae shift bacterial movement toward Lévy flight patterns, enhancing encounter rates and self‐aggregation. This microecological manipulation reduces energy costs, strengthens functions such as pollutant removal and system stability.
Luyu Zhang +7 more
wiley +1 more source
Mean-field equation for a stochastic many-particle model of quorum-sensing microbial populations
, 2018 We prove a mean-field equation for the dynamics of quorum-sensing microbial populations. In the stochastic many-particle process, individuals of a population produce public good molecules to different degrees.
Frey, Erwin +2 more
core
Advanced Science, EarlyView.Butyrate—via epigenetic modulation of the histone core—rebalance dysregulated macrophage function and promotes wound healing under persisting hostile conditions of diabetic mice. Additionally, butyrate harmonizes macrophage interactions with keratinocytes and fibroblasts as well as breaks the vicious cycle of inflammation in chronic wounds by restoring
Karmveer Singh +11 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals that specific genetic variations in gut‐residing Saccharomyces cerevisiae significantly extend healthspan and lifespan in Drosophila melanogaster. These mutants rejuvenate aged intestinal metabolism, upregulate mitochondrial proteins, and enhance energy pathways.
Liying Wang +11 more
wiley +1 more source