Results 151 to 160 of about 535,232 (307)

Advances in Electrochemical Urea Biosensors: Trends and Future Prospects

open access: yesAdvanced Sensor Research, EarlyView.
This review explores advances in enzymatic and non‐enzymatic biosensors, emphasizing electrochemical detection, material innovations, and IoT integration for real‐time tracking. Key challenges and future opportunities in enhancing sensitivity, selectivity, and portability are highlighted, showcasing biosensors as promising tools for next‐generation ...
Samar Shurbaji   +6 more
wiley   +1 more source

Electro‐Conductive Silver‐Coated Polyamide‐Imide Membranes for Sustainable Water Treatment

open access: yesAdvanced Sustainable Systems, EarlyView.
This study reports the development of a silver‐coated, electro‐conductive ultrafiltration membrane supported on polyamide‐imide. Using a simple and scalable spray‐coating method, the membrane achieved a high electrical conductivity of 2.215 × 10−5 S cm−1.
Zahra Zandi   +11 more
wiley   +1 more source

Combining genomic data and infection estimates to characterize the complex dynamics of SARS-CoV-2 Omicron variants in the US

open access: yesCell Reports
Summary: Omicron surged as a variant of concern in late 2021. Several distinct Omicron variants appeared and overtook each other. We combined variant frequencies and infection estimates from a nowcasting model for each US state to estimate variant ...
Rafael Lopes   +10 more
doaj   +1 more source

Therapeutic Antibodies for Mosquito‐Borne Orthoflavivirus Infections: Discovery, Engineering Approaches, and Advances in mRNA‐Based Delivery Systems

open access: yesAdvanced Therapeutics, EarlyView.
This review explores how antibody engineering and display technologies are driving therapeutic advances against mosquito‐borne orthoflaviviruses such as Zika, dengue, and yellow fever viruses. It highlights diverse neutralizing targets on the envelope protein, including the conserved fusion loop, and discusses how Fc engineering, rational antigen ...
Ana Clara Barbosa Antonelli   +5 more
wiley   +1 more source

CRISPR‐MI and scRNA‐Seq Reveal TREM2's Function in Monocyte Infiltration and Macrophage Apoptosis During Abdominal Aortic Aneurysm Development

open access: yesAdvanced Science, EarlyView.
A method is developed for conducting genome‐wide CRISPR/Cas9 screening of monocyte infiltration in vivo (CRISPR‐MI) that is easily adaptable across a variety of disease models. Through the combination of CRISPR‐MI and scRNA‐Seq, this study discovers that Trem2 is a key regulator of early monocyte infiltration in abdominal aortic aneurysm (AAA ...
Haocheng Lu   +30 more
wiley   +1 more source

Mean-field equation for a stochastic many-particle model of quorum-sensing microbial populations

open access: yes, 2018
We prove a mean-field equation for the dynamics of quorum-sensing microbial populations. In the stochastic many-particle process, individuals of a population produce public good molecules to different degrees.
Frey, Erwin   +2 more
core  

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian   +26 more
wiley   +1 more source

Exploring Functionally Enhanced BLP‐Trained Macrophage Subpopulations in S. Aureus Infection: Underlying Mechanisms and Therapeutic Significance

open access: yesAdvanced Science, EarlyView.
BLP‐trained macrophages show augmented resistance to infection, but their mechanisms remain unclear. scRNA‐seq identified 13 BMDM subsets, with two novel anti‐inflammatory/antibacterial subpopulations (C5/C7) emerging post‐BLP training. BLP training activates NRF2, attenuates oxidative stress/ferroptosis, and boosts glycolysis/OXPHOS. Adoptive transfer
Yantong Wan   +13 more
wiley   +1 more source

Editorial: Evolution of Animal Microbial Communities in Response to Environmental Stress

open access: yesFrontiers in Microbiology, 2022
Teresa Nogueira   +4 more
doaj   +1 more source

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