Results 201 to 210 of about 369,608 (276)

What lurks in the dark? An innovative framework for studying diverse wild insect microbiota. [PDF]

open access: yesMicrobiome
Nowak KH   +7 more
europepmc   +1 more source

Development of Age‐ and Sex‐Specific Metabolomics‐Based Biological Ageing Clocks for 10‐Year Mortality Prediction

open access: yesAdvanced Science, EarlyView.
Metabolomics‐based ageing clocks developed using blood biomarkers from over 215 000 European adults, improved the prediction of 10‐year all‐cause mortality compared to traditional models. Biological age acceleration is associated with higher mortality risk, as each additional year of metabolic age corresponded to at least 8% increased risk. These tools
Lei Peng   +4 more
wiley   +1 more source

Microbial diversity in drug-naïve Parkinson's disease patients. [PDF]

open access: yesPLoS One
Papić E   +13 more
europepmc   +1 more source

Quantification of Antibiotic Diffusion in Biofilms Using Gold Nanostar Surface‐enhanced Raman Spectroscopy

open access: yesAdvanced Science, EarlyView.
Gold nanostar‐enhanced Raman spectroscopy (SERS) enables real‐time, label‐free tracking of levofloxacin diffusion in intact biofilms. Nanostars embedded 16 µm below the surface detect drug arrival over time, revealing the impact of the biofilm matrix on antibiotic transport. Abstract The increased resistance to antibiotics shown by bacteria in biofilms
Wafaa Aljuhani   +4 more
wiley   +1 more source

Bacteriophage as an anti-biofilm agent against Pseudomonas aeruginosa from wound infection. [PDF]

open access: yesPLoS One
Shrestha P   +6 more
europepmc   +1 more source

CDK4/6 Inhibitor Priming Enhances PD‐1 Blockade via Sellhi Neutrophil‐Induced Stat5a+ Progenitor Exhausted CD8+ T Cell

open access: yesAdvanced Science, EarlyView.
Activated tumor‐intrinsic cyclin D1‐CDK4/6 signaling attenuates lymphocyte infiltration, and consequently, and immunotherapy resistance in HNSCC. It is discovered that brief CDK4/6i priming before anti‐PD‐1 results in enhanced durability of ICB response durability through Stat5a+ progenitor exhausted CD8+ T cells induced by IL15‐secreted Sell(hi ...
Yu Zhang   +13 more
wiley   +1 more source

Targeting of the CD161 Inhibitory Receptor Enhances Bone‐Marrow‐Resident Memory CD8+ T‐Cell‐Mediated Immunity against Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
CD161 is identified as a novel inhibitory receptor on bone marrow (BM)‐resident CD8⁺ T cells in multiple myeloma (MM). Through interaction with its ligand CLEC2D, CD161 impairs T‐cell function and promotes immune suppression. Blockade of CD161 restores tissue residency and cytotoxicity of CD8⁺ T cells and enhances chimeric antigen receptor T‐cell (CAR ...
Liwen Wang   +16 more
wiley   +1 more source

Cross-Contamination of Foodborne Pathogens During Juice Processing. [PDF]

open access: yesBiology (Basel)
Neggazi I   +3 more
europepmc   +1 more source

A Reaction‐Diffusion Frame for Accessing Metabolic O2 Fluxes in Single Microalgal Cells with Low‐Cost Wide‐Field Imaging of Nanosensor Luminescence Lifetime

open access: yesAdvanced Science, EarlyView.
Individual Chlamydomonas reinhardtii (C. reinhardtii) living cells on an agarose pad containing luminescent O2 nanosensors are imaged with a simple wide‐field protocol of lifetime imaging. The resulting maps of phosphorescence lifetime are analyzed within a reaction‐diffusion frame to access the distribution of metabolic O2 fluxes generated by single ...
Hélène Merceron   +11 more
wiley   +1 more source

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