Results 241 to 250 of about 535,232 (307)

A Sampling Method Considering Body Size for Detecting the Associated Microbes in Plankton Populations: A Case Study, Using the Bloom-Forming Cyanobacteria, <i>Microcystis</i>. [PDF]

Biology (Basel)
Lin L, Gan N, Huang L, Song L, Zhao L.
europepmc   +1 more source

USP11‐PGAM5 Axis Promotes Neurotoxic Astrocyte Reactivity by Aggravating the mtDNA‐cGAS‐STING Pathway After Intracerebral Hemorrhage

Advanced Science, EarlyView.
This study reveals that the deubiquitinase USP11 stabilizes PGAM5, triggering neurotoxic astrocyte transformation after intracerebral hemorrhage. PGAM5 promotes mPTP opening and Drp1 dephosphorylation, synergistically amplifying mtDNA leakage into the cytosol and leading to cGAS–STING hyperactivation.
Jiaqing He, Zijuan Qin, Yaning Cai, Haixiao Liu, Tinghao Wang, Qing Hu, Yanni Xu, Pan Yang, Xun Wu, Yan Qu, Wei Guo   +10 more
wiley   +1 more source

Increasing Prevalence of Plant-Fungal Symbiosis Across Two Centuries of Environmental Change. [PDF]

Glob Chang Biol
Fowler JC, Moutouama J, Miller TEX.
europepmc   +1 more source

The Circadian Transcription Factor CLOCK Modulates Oxidative Stress Resistance via the ACHL–Relish Axis in Drosophila

Advanced Science, EarlyView.
This study identifies the circadian transcription factor CLOCK (CLK) as a key regulator of oxidative stress resistance in fruit flies. CLK controls immune responses by driving rhythmic transcription of an RNA‐binding protein‐Achilles (ACHL) in the fly brain, which post‐transcriptionally represses the NF‐κB homolog Relish, limiting immune activation and
Xu Liu, Jiajia Fang, Dawei Cheng, Wei Luan, Yan Lv, Wen Hu, Lei Pan, Yong Zhang   +7 more
wiley   +1 more source

STREAK method: a teaching practice that supports students in a mixed classroom community. [PDF]

J Microbiol Biol Educ
McElmurry K, Saunders DRD, Little KP, Steel JJ.   +3 more
europepmc   +1 more source

Integrative Omics Defines Metabolic Biomarkers and Genetic Regulatory Mechanisms of Mortality Risk

Advanced Science, EarlyView.
Understanding mortality mechanisms remains a fundamental challenge. Through multi‐omics analysis of a three‐generation chicken model, are identified 45,585 mQTLs and establish a 16‐metabolite predictor of mortality. An inflammation‐growth trade‐off and evolutionarily conserved pathways involving butyrate–microbiota interactions and L‐cysteine's dual ...
Peihao Liu, Bingxing An, Jumei Zheng, Qiao Wang, Zhirui Yang, Zhengda Li, Dawei Liu, Fan Ying, Jie Wen, Lingzhao Fang, Guiping Zhao   +10 more
wiley   +1 more source

Immune repertoire profiling and T cell dysregulation in Peripheral Blood Mononuclear Cells of Type 2 diabetic patients. [PDF]

PLoS One
Bi Z, Wang F, Wang S, Fang Z.
europepmc   +1 more source

Colored Plastic Pollution Reshapes Aquatic Microbial Community and Resistance Profile via Divergent Pseudonatural Dissolved Organic Matter

Advanced Science, EarlyView.
By altering the quantity and chemical composition of polyethylene‐derived dissolved organic matter, plastic color dynamically regulates bacterial metabolic interactions, thereby reshaping community resistance expression and facilitating the dissemination of antibiotic resistance.
Shuting Fang, Shuqin Liu, Jingui Huang, Yiquan Huang, Chao Chen, Qijun Ruan, Pengran Guo, Gangfeng Ouyang   +7 more
wiley   +1 more source

Quantitative real-time PCR detection of <i>Porphyromonas gingivalis</i> and <i>Filifactor alocis</i> in peri-implantitis. [PDF]

J Med Microbiol
Fragkioudakis I, Konstantopoulos G, Kottaridi C, Batas L, Sakellari D.   +4 more
europepmc   +1 more source

SUPER: Upcycling Genetic Parts for Precise Gene Expression Control, Leakage Minimization, and Genetic Circuit Stability

Advanced Science, EarlyView.
To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo, Dongwon Park, Woosub Shin, Jongmin Kim   +3 more
wiley   +1 more source