Results 221 to 230 of about 919,747 (358)

Cell Membrane‐Coated Lipid Nanoparticles for Drug Delivery

Aggregate, EarlyView.
This review highlights recent progress in cell membrane‐coated lipid nanoparticles (CMC‐LNPs), focusing on their design, preparation methods, functional integration, and biomedical applications. It discusses various types of LNPs and coating strategies, characterization techniques, therapeutic functions, and applications.
Moataz B. Zewail, Guangze Yang, Yilong Fan, Yue Hui, Chun‐Xia Zhao, Yun Liu   +5 more
wiley   +1 more source

Development of an Improved Thiosulfate-Utilizing Denitrifying Bacteria-Based Ecotoxicity Test with High Detection Sensitivity and Reproducibility. [PDF]

Toxics
Eom H.
europepmc   +1 more source

Multifunctional Framework Nucleic Acid Vehicle for Antibiotic Sensitization and Treatment of Methicillin‐Resistant Staphylococcus aureus

Aggregate, EarlyView.
A self‐assembling, aggregation‐enhanced tetrahedral DNA nanostructure (tFNA), termed TACs, enables localized accumulation and sustained release of ceftriaxone while co‐delivering antisense oligonucleotides that silence mecA, reduce PBP2a expression, and restore β‐lactam susceptibility in MRSA.
Yicheng Zhao, Jingyi Si, Shisong Jing, Bingmei Wang, Yueshan Xu, Jiyu Guan, Quan Liu, Jianlei Shen, Min Lv, Li Wang, Changfeng Zhu   +10 more
wiley   +1 more source

Enhanced Detection of Bacterial Ocular Pathogens: A Comparative Study of Broad-Range Real-Time PCR and Conventional Culture Methods. [PDF]

Diagnostics (Basel)
Park S, Kim K, Lee Y, Ryoo N.
europepmc   +1 more source

Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils

Aggregate, EarlyView.
This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky, Olesya V. Stepanenko, Olga V. Stepanenko, Anna I. Sulatskaya   +3 more
wiley   +1 more source

Higher temperature sensitivity of forest soil methane oxidation in colder climates. [PDF]

Nat Commun
Jiang B, Chen H, Wei Z, Zhang J, Guo M, Yang T, Zhou X.   +6 more
europepmc   +1 more source

Modeling heterogeneity in large‐scale bioreactors using the method of moments with a truncated normal distribution

AIChE Journal, EarlyView.
ABSTRACT Large‐scale bioreactors in industrial bioprocesses pose challenges due to extracellular concentration gradients and intracellular heterogeneity. This study introduces a novel approach integrating the method of moments with truncated normal distributions (MM‐TND) to model intracellular heterogeneity while maintaining computational feasibility ...
Ittisak Promma, Marc G. Aucoin, Nasser Mohieddin Abukhdeir, Hector Budman   +3 more
wiley   +1 more source

Causal associations between gut microbiota and rheumatoid arthritis: A two-sample Mendelian randomization study. [PDF]

Medicine (Baltimore)
Wei F, Zhao M, Sun X, Ma H, Yin H, Shen X.   +5 more
europepmc   +1 more source

AI‐Enhanced Surface‐Enhanced Raman Scattering for Accurate and Sensitive Biomedical Sensing

Advanced Intelligent Discovery, EarlyView.
AI‐SERS advances spectral interpretation with greater precision and speed, enhancing molecular detection, biomedical analysis, and imaging. This review explores its essential contributions to biofluid analysis, disease identification, therapeutic agent evaluation, and high‐resolution biomedical imaging, aiding diagnostic decision‐making.
Seungki Lee, Rowoon Park, Ho Sang Jung
wiley   +1 more source

The gut-liver axis plays a limited role in mediating the liver's heat susceptibility of Chinese giant salamander. [PDF]

BMC Genomics
Zhai R, Zhao C, Chang L, Liu J, Zhao T, Jiang J, Zhu W.   +6 more
europepmc   +1 more source