Results 241 to 250 of about 935,221 (361)

Near‐Freezing‐Temperature Golgi Neuronal Staining for X‐ray Imaging of Human Brain

Advanced Science, EarlyView.
A near‐freezing temperature staining strategy, combined with a mercury chloride‐based method, effectively preserves delicate neuronal structures in post‐mortem frozen human brain tissues by minimizing autolysis. This approach enables uniform labeling across centimeter‐scale slices and, when integrated with synchrotron‐based X‐ray microscopy, achieves ...
Feng Zhou, Qiaowei Tang, Xin Yan, Chao Ma, Yu Zhang, Jichao Zhang, Qian Li, Lihua Wang, Jun Hu, Xiaoqing Cai, Jiang Li, Ying Zhu, Chunhai Fan   +12 more
wiley   +1 more source

Potassium Fulvate Alleviates Salt-Alkali Stress and Promotes Comprehensive Growth of Oats in Saline-Alkali Soils of the Qaidam Basin. [PDF]

Plants (Basel)
Jin X, Wang J, Liu X, Chang J, Li C, Lu G.   +5 more
europepmc   +1 more source

Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling

Advanced Science, EarlyView.
The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen, Fugui Zhang, Yifei Xiao, Xuejun Jiang, Zhiqian Yan, Jinyi Wang, Xiting Lv, Jialu Cui, Linna Ha, Hui Chen, Yongkang Dang, Zifei Qin, Jing Yang, Baojian Wu   +13 more
wiley   +1 more source

Advancing microbial risk assessment: perspectives from the evolution of detection technologies. [PDF]

NPJ Sci Food
Xiao L, Li Z, Dou X, Long Y, Li Z, Liu Y, Dong Q.   +6 more
europepmc   +1 more source

Gut Parabacteroides distasonis‐derived Indole‐3‐Acetic Acid Promotes Phospholipid Remodeling and Enhances Ferroptosis Sensitivity via the AhR‐FASN Axis in Bladder Cancer

Advanced Science, EarlyView.
Indole‐3‐acetic acid (3‐IAA) derived from gut P. distasonis binds to AhR in bladder cancer cells and downregulates FASN transcription, thereby increasing sensitivity to ferroptosis and suppressing the development of bladder tumors. Specifically, 3‐IAA treatment leads to an increase in the proportion of PC/PE‐PUFAs and a decrease in the proportions of ...
Weijia Li, Wentai Shangguan, Wenxue Huang, Jie Zhao, Yuexuan Zhu, Ming Xie, Yao Yu, Qishen Yang, Jun Zheng, Lin Yang, Qi Sun, Leqian Li, Xinhang Shi, Yongyuan Xiao, Hai Huang, Bisheng Cheng, Peng Wu   +16 more
wiley   +1 more source

Integrative study of pulmonary microbiome and clinical diagnosis in pulmonary tuberculosis patients. [PDF]

Microbiol Spectr
Sun H, Chen Q, Zhang D, Hu L, Li S, Lu M, Wang Y, Su H, Gao Y, Guo J, Zhao Y, Du J, Liu C, Xia H, Xu Y, Ge X, Yang Q.   +16 more
europepmc   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

Development and evaluation of a triplex real-time PCR assay for enhanced plague diagnostics in Madagascar. [PDF]

PLoS Negl Trop Dis
Ramasindrazana B, Rahalison ZA, Gauthier P, Mikaty G, Bodoarison ZI, Maminirina LA, Rahajandraibe S, Randriamanantsoa MG, Kayoko G, Manuguerra JC, Le Guern AS, Rasamindrakotroka AJ, Rajerison M.   +12 more
europepmc   +1 more source

Commensal Viruses Promote Intestinal Stem Cell Regeneration Following Radiation Damage by Inhibiting Hyperactivation of RIG‐I and Notch Signals

Advanced Science, EarlyView.
Ionizing radiation disrupts gut virome and bacteriome. Gut commensal viruses protect against intestinal damage and promote stem cell regeneration by inhibiting hyperactivation of RIG‐I and Notch signaling in stem cells. Fecal virome transplantation (FVT) from healthy donors can serve as a potential therapeutic intervention by enriching phages targeting
Xiaotong Zhao, Yu Cai, Yujia Hou, Yanjin Wu, Tingting Wei, Lili Li, Zhaojun Duan, Xinran Lu, Jiahui Meng, Haitao Zhou, Qin Wang, Jinhan Wang, Chang Xu, Liqing Du, Saijun Fan, Feng Wang, Qiang Liu, Yang Liu   +17 more
wiley   +1 more source

MGV-seq: a sensitive and culture-independent method for detecting microbial genetic variation. [PDF]

Front Microbiol
Li L, Kong W, Sun J, Jiang Y, Li T, Xia Z, Zhou J, Fang Z, Chen L, Feng S, Song H, Xiao H, Zhang B, Fang B, Peng H, Gao L.   +15 more
europepmc   +1 more source