Results 241 to 250 of about 948,954 (362)

CLAE: A High‐Fidelity Nanopore Sequencing Strategy for Read‐Level Viral Variant Detection and Environmental RNA Virus Discovery

Advanced Science, EarlyView.
High‐fidelity Nanopore sequencing offers a cost‐effective, portable path to uncovering viral dark matter in complex environments—but suffers from severe read‐length bias, low throughput, and limited accuracy. This study traces these limitations to core biochemical barriers and introduces CLAE, a foundational high‐fidelity platform that enables accurate,
Hannah Yu, Sarah Golconda, Ga‐Eun Lee, Dantong Xue, Guillermo Domínguez‐Huerta, James M. Wainaina, Benjamin Bolduc, Shashanka Murthy, Shihyoung Kim, Seth Faith, Shan‐Lu Liu, Jiyoung Lee, Michael Oglesbee, Matthew B Sullivan, Sanggu Kim   +14 more
wiley   +1 more source

Examination of unique volatile organic compound signatures in nasopharyngeal test swab viral transport media using an electronic nose. [PDF]

PLoS One
Swanson B, Bishop-Royse J, Keshavarzian A, Balk R, Bhushan A, Moy J, Landay A, Julion W, Mehta J, Arrieta M, Behun D, Bowlen M, Kang M.   +12 more
europepmc   +1 more source

Depth‐Dependence Changes in Soil Stoichiometry in China's Croplands Over the Past Four Decades

Advanced Science, EarlyView.
This study reveals depth‐dependent changes in soil C:N:P ratios across Chinese croplands over four decades. Changes in stoichiometry vary markedly between topsoil and subsoil, with initial soil C:N:P ratios playing a key role in determining their trajectories.
Xiaodong Sun, Zhenghu Zhou, Yiqi Luo, Qingzhu Gao, Hu Li, Shuo Liu, Minggang Xu, Yu'e Li, Andong Cai   +8 more
wiley   +1 more source

A Comprehensive Oncological Biomarker Framework Guiding Precision Medicine. [PDF]

Biomolecules
Mokhtari RB, Sambi M, Shekari F, Satari K, Ghafoury R, Ashayeri N, Eversole P, Baluch N, Harless WW, Muscarella LA, Yeger H, Das B, Szewczuk MR, Chakraborty S.   +13 more
europepmc   +1 more source

Disruption of Gut Microbiota‐Mediated De Novo NAD+ Synthesis Contributes to the Development of Polycystic Ovary Syndrome

Advanced Science, EarlyView.
This study demonstrates that patients with PCOS exhibit altered gut microbial profiles, and FMT from PCOS patients induces PCOS‐like symptoms in mice. Specifically, gut dysbiosis reduces 3‐HAA levels in the context of PCOS. Administration of 3‐HAA to mice alleviates PCOS by promoting de novo NAD+ synthesis.
Ke Chen, Huafeng Geng, Yang Zheng, Hongyang Xie, Rui Qin, Junyang Chen, Cong Ye   +6 more
wiley   +1 more source

Utility of microbial cell-free DNA sequencing in the diagnosis of mycobacterial infections in a quaternary care center. [PDF]

Antimicrob Steward Healthc Epidemiol
Centeno FH, Lasco T, Hamdi AM, Al Mohajer M.   +3 more
europepmc   +1 more source

Dynamic Profiling of Lipoteichoic Acid (LTA) and/or Lipopolysaccharide (LPS) Positive Extracellular Vesicles in Plasma as Diagnostic and Prognostic Biomarkers for Bacterial Infection

Advanced Science, EarlyView.
Using nano‐flow cytometry, this study analyzes the dynamic characteristics of lipoteichoic acid (LTA) and/or lipopolysaccharide (LPS) positive extracellular vesicles in the bloodstream of patients with bacterial infections, providing promising biomarkers for rapid and accurate diagnosis.
Qianqian Gao, Wenwu Zhou, Nadira Nurxat, Ke Xu, Yunyun Xu, Wei Li, Tianchi Chen, Cong Hu, Liang Dong, Qian Liu, Min Li   +10 more
wiley   +1 more source

Correlation Between Microbial Toxin Levels and Biochemical Markers of Organ Damage in ICU Patients. [PDF]

Cureus
Thummala H, Sangeeta S, Bhuyar BK, Rapeti LSK, Kandimalla R.   +4 more
europepmc   +1 more source

Constitutive Androstane Receptor in Macrophages Regulates Toll‐Like Receptor 4‐Mediated Innate Immune Responses Against Endotoxemic Liver Injury

Advanced Science, EarlyView.
The present study uncovers a novel role of constitutive androstane receptor (CAR) in inflammation‐mediated damage. CAR activation in macrophages inhibits proinflammatory macrophages by interacting with Tlr4, which protects against endotoxemic liver injury.
Renjie Cao, Tingting Zhao, Ying Wang, Shaofei Song, Yuan Li, Mengling Hou, Yanxin Zhang, Sengpeng Wong, Siqi Wang, Yuran Wang, Hong Peng, Min Huang, Yiming Jiang   +12 more
wiley   +1 more source

Highly Sensitive SOI-TFET Gas Sensor Utilizing Tailored Conducting Polymers for Selective Molecular Detection and Microbial Biosensing Integration. [PDF]

Biosensors (Basel)
Anvarifard MK, Ramezani Z.
europepmc   +1 more source