Results 251 to 260 of about 948,954 (362)

A Genetically Encoded Biosensor for Characterizing Transport and Metabolism of Glutarate

Advanced Science, EarlyView.
Here, a genetically encoded glutarate biosensor, Glusor, is developed based on transcriptional regulator CsiR. Glusor can quantify glutarate concentrations with good accuracy and precision. Then, the role of KgtP and YnfM are identified and characterized by using Glusor. Glusor also allows glutarate spatiotemporal resolution in live cells, facilitating
Kaiyu Gao, Hui Zhang, Yidong Liu, Xianzhi Xu, Wei Liu, Zhaoqi Kang, Rong Xu, Shuang Hou, Ping Han, Chuanjuan Lü, Cuiqing Ma, Ping Xu, Chao Gao   +12 more
wiley   +1 more source

Oral and fecal microbiome alterations in pancreatic cancer: insights into potential diagnostic biomarkers. [PDF]

BMC Microbiol
Tavanaeian S, Feizabadi MM, Falsafi S, Aghdaei HA, Houri H.   +4 more
europepmc   +1 more source

A Lipid with Lewis Pair‐Mediated Targeting and Multiple Stimuli‐Responsive Delivery of Antibiotics for Bacterial Infections

Advanced Science, EarlyView.
Lewis pair‐integrated lipids (Lp‐lipids), combining targeted delivery and stimuli‐responsive are developed for antibiotic delivery. These lipids form nanoparticles that bind biofilms via boronate ester bonds and respond to acidic pH, H2O2, and ATP, enabling controlled drug release.
Xiaojian Yan, Lei Hua, Hongping Wan, Yong Liu, Tao Jin, Yicen Ge, Michael R Hamblin, Mahdi Karimi, Xinghong Zhao, Yan Hu, Linqi Shi, Yuanfeng Li   +11 more
wiley   +1 more source

The Association of Wagner Classification, Microbial Resistance, Immune Markers, and Glycemic Control With Diabetic Foot Ulcer Severity: A Multi-disciplinary Approach to Predict Severity and Outcome. [PDF]

Cureus
Saleem MN, Mir A, Ullah U, Talha M, Nawaz H, Rehman A, Ullah R.   +6 more
europepmc   +1 more source

An Automated Lab‐On‐A‐Chip Approach for Pollen Tube Growth Manipulation in a Controlled Chemical Environment

Advanced Science, EarlyView.
Here, a microfluidic‐based robotic lab‐on‐a‐chip (LoC) device is presented for automated, continuous‐flow investigation and manipulation of single pollen tube growth under precisely controlled chemical gradients. This closed‐loop system streamlines data collection and analysis while enhancing experimental precision compared to manual methods ...
Jiawei Zhu, Marta Belloli, João P. Vale, Vitaly Pustovalov, Peter Fischer, Hannes Vogler, Tiago S. Mayor, Salvador Pané, Semih Sevim, Ueli Grossniklaus, Bradley J. Nelson   +10 more
wiley   +1 more source

Identifying the drivers of microbial community changes and interactions in polluted coastal sediments. [PDF]

Environ Microbiome
Ramljak A, Jurburg S, Chatzinotas A, Lučić M, Žižek M, Babić I, Udiković-Kolić N, Petrić I.   +7 more
europepmc   +1 more source

Big Data and AI‐Powered Modeling: A Pathway to Sustainable Precision Animal Nutrition

Advanced Science, EarlyView.
This review summarizes the current landscape of big data and AI‐powered modeling in animal nutrition, covering techniques including intelligent data acquisition, data augmentation, explainable machine learning, heuristic algorithms, and life cycle assessment‐based sustainability evaluation.
Shuai Zhang, Changhua Lai, Jinbiao Zhao, Junjun Wang   +3 more
wiley   +1 more source

Colorectal cancer molecular profiling: Opportunities for early detection. [PDF]

Clin Transl Med
Sala A, van den Driest L, Rattray NJW, Johnson CH, Cameron JM, Khan SA, Palmer DS, Baker MJ.   +7 more
europepmc   +1 more source

Directed Self‐Assembly of Magnetic Bioceramic Deep Inside Dentinal Tubules May Alleviate Dental Hypersensitivity

Advanced Science, EarlyView.
Magnetically guided bioceramic nanoparticles (“CalBots”) achieve deep dentinal tubule occlusion via directed self‐assembly under externally applied magnetic field. Various visualization techniques and a novel mouse behavioral assay indicate that CalBot‐induced plugs may reduce dentinal sensitivity, offering a promising strategy for future dentin ...
Shanmukh Peddi, Prajwal Hegde, Prannay Reddy, Anaxee Barman, Arnab Barik, Debayan Dasgupta, Ambarish Ghosh   +6 more
wiley   +1 more source

The Comparison of Diagnostic Performance Between Next-Generation Sequencing of Blood and Tissues for Primary Spinal Infections. [PDF]

Global Spine J
Liu C, Long J, Li Y, Leng X, Zhang J, Chen S, Fu J, Li C, Zhou Y, Feng C, Huang B.   +10 more
europepmc   +1 more source