Results 271 to 280 of about 935,221 (361)

A Refined Adaptive Laboratory Evolution Strategy With Biosensor‐Assisted Selection Resolves the Tolerance–Efficiency Trade‐Off in Toxic Chemical Biosynthesis

open access: yesAdvanced Science, EarlyView.
This study presents a refined adaptive laboratory evolution (ALE) strategy to resolve the trade‐off between tolerance and biosynthetic efficiency in toxic chemical production. Combining in vivo mutagenesis, microdroplet‐based evolution, and biosensor‐assisted selection, this strategy rapidly yields robust “win‐win” phenotypes.
Yufei Zhang   +7 more
wiley   +1 more source

Protein Spatial Structure Meets Artificial Intelligence: Revolutionizing Drug Synergy–Antagonism in Precision Medicine

open access: yesAdvanced Science, EarlyView.
This review comprehensively examines the applications of protein three‐dimensional structures and artificial intelligence in investigating drug synergistic and antagonistic effects. The research findings provide compelling evidence for the precision treatment of cancer and metabolic diseases, thereby promoting the development of personalized medicine ...
Anqi Lin   +11 more
wiley   +1 more source

The impact of gut microbiome modulation on anthropometric indices in metabolic syndrome: an umbrella review. [PDF]

open access: yesAnn Med Surg (Lond)
Aleali MS   +14 more
europepmc   +1 more source

In-vitro antimicrobial activity of Jatropha variegata Vahl. (Euphorbiaceae) against some pathogenic microbes isolated from clinical samples in Ibb City, Yemen. [PDF]

open access: yesSci Rep
Esmail A   +10 more
europepmc   +1 more source

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