Results 41 to 50 of about 125,399 (279)

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

Evaluation of conjunctival bacterial flora in patients with Stevens-Johnson Syndrome

Clinics, 2014
OBJECTIVE: To determine the conjunctival bacterial flora present in patients with Stevens-Johnson syndrome. METHODS: A prospective study of the conjunctival bacterial flora was performed in 41 eyes of 22 patients with Stevens-Johnson syndrome.
Luciana Frizon, Marília Cavalcante Araújo, Larissa Andrade, Maria Cecília Zorat Yu, Tais Hitomi Wakamatsu, Ana Luisa Höfling-Lima, José Álvaro Pereira Gomes   +6 more
doaj   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

Determination of Streptococcus sp. and Candida albicans in the oral cavity of patients undergoing bone marrow transplantation

Journal of Oral Research, 2021
Introduction: Chemotherapy can lead to an imbalance in the ecosystem of the oral cavity, allowing the development of mucositis in the immunosuppression phase due to interaction with microbial agents.
Evelin Bachmeier, María Elena Migueles Goitea, Jorge Alberto Linares, Fernando Martín Wietz, Sol Jarchum, Gustavo Jarchum, Mabel Noemí Brunotto, Marcelo Adrián Mazzeo   +7 more
doaj   +1 more source

Anti-microbial efficacy of Vanilla planifolia leaf extract against common oral micro-biomes

Journal of Oral and Maxillofacial Pathology, 2022
Introduction:Over the past century, several antibiotics have been discovered and used to treat various microbial diseases. However, over the past few decades, with the emergence of anti-microbial resistant strains of microbiomes, it has become increasingly necessary to discover and develop alternative anti-microbial agents.
Kamath, Ajith K., Nasim, Iffat, Muralidharan, NP, Kothuri, Ravalika N.   +3 more
openaire   +2 more sources

Toward Design Principles for Biomolecular Condensates for Metabolic Pathways

Advanced Biology, EarlyView.
Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André, Nikita Rehnberg, Ankush Garg, Magnus Kjærgaard   +3 more
wiley   +1 more source

The microbiology, epidemiology, risk factors, and clinical therapy of candidemia in burn patients hospitalized in Velayat Teaching Hospital, Rasht, northern Iran

Iranian Journal of Microbiology
Background and Objectives: The study aimed to investigate the epidemiology and clinical therapy of candidemia in burn patients hospitalized in Velayat Hospital, Rasht, Iran.
Zahra Rafat, Davoud Roostaei, Mohammadreza Mobayen, Hamid Salehiniya, Parimah Pournasrolah   +4 more
doaj   +1 more source

In Vitro Susceptibility Testing of Rifampin Against Acinetobacter Baumannii: Comparison of Disk Diffusion, Agar Dilution, and E-test

Erciyes Medical Journal, 2019
Objective: Resistance against a wide variety of antibiotics is one of the prominent characteristics of Acinetobacter baumannii. The purpose of this study was to investigate the in vitro susceptibility testing of A.
Mojtaba Varshochi, Alka Hasani, Seyed Jalaledin Derakhshanfar, Zhinous Bayatmakoo, Fatemeh Ravanbakhsh Ghavghani, Parinaz Poorshahverdi, Masoud Nouri-Vaskeh   +6 more
doaj   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Direct Ink Writing of Conductive Hydrogels

Advanced Functional Materials, EarlyView.
This review examines the use of direct ink writing (DIW) for fabricating conductive hydrogels with customizable 3D structures. It outlines the rheological requirements for successful DIW, followed by an exploration of the materials and ink formulations used to impart electronic and/or ionic conductivity to hydrogels while maintaining printability ...
Monica Ho, Aline Braz Ramirez, Negar Akbarnia, Eric Croiset, Elisabeth Prince, Gerald G. Fuller, Milad Kamkar   +6 more
wiley   +1 more source